| Literature DB >> 825379 |
T Hökfelt, K Fuxe, O Johansson, S Jeffcoate, N White.
Abstract
With the indirect immunofluorescence technique TRH-containing nerve terminals were found in the medial part of the external layer of the median eminence, the dorsomedial nucleus and the perifornical area, in extrahypothalmic nuclei such as nucleus accumbens, the lateral septal nucleus and in several motor nuclei of the brain stem and spinal cord. These findings suggest that TRH may act both as a hormone, released into the portal vessels, as well as a neurotransmitter or modulator, released at synapses in discrete regions of the brain and spinal cord.Entities:
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Year: 1975 PMID： 825379 DOI： 10.1016/0014-2999(75)90269-1
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432