Literature DB >> 8252411

Vasoactive intestinal peptide: a growth promoter in neuroblastoma cells.

Y Wollman1, G Lilling, M N Goldstein, M Fridkin, I Gozes.   

Abstract

Vasoactive intestinal peptide (VIP) is a neuromodulator, growth regulator and secretagogue for neuronal survival factors. Moreover, VIP has been suggested to be a mitogenic factor for embryonic neurons in the sympathetic nervous system. We now show that VIP had mitogenic activity in a human neuroblastoma cell line (NMB), as measured by cell number and thymidine incorporation. This mitogenic activity was dose dependent and was decreased with culture maturation. Northern blot analysis revealed VIP mRNA transcripts in this cell line suggesting an autocrine role for VIP in neurogenesis.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8252411     DOI： 10.1016/0006-8993(93)90100-2

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  9 in total

1.  VIP, from gene to behavior and back: summarizing my 25 years of research.

Authors:  Illana Gozes
Journal:  J Mol Neurosci       Date:  2008-07-08       Impact factor: 3.444

Review 2.  A VIP hybrid antagonist: from developmental neurobiology to clinical applications.

Authors:  I Gozes; M Fridkin; D E Brenneman
Journal:  Cell Mol Neurobiol       Date:  1995-12       Impact factor: 5.046

3.  Identification of VIP/PACAP receptors on rat astrocytes using antisense oligodeoxynucleotides.

Authors:  O Ashur-Fabian; E Giladi; D E Brenneman; I Gozes
Journal:  J Mol Neurosci       Date:  1997-12       Impact factor: 3.444

Review 4.  Regulation of VIP gene expression in general. Human lung cancer cells in particular.

Authors:  A Davidson; T W Moody; I Gozes
Journal:  J Mol Neurosci       Date:  1996       Impact factor: 3.444

Review 5.  Activity-dependent neurotrophic factor (ADNF). An extracellular neuroprotective chaperonin?

Authors:  I Gozes; D E Brenneman
Journal:  J Mol Neurosci       Date:  1996       Impact factor: 3.444

Review 6.  VIP as a cell-growth and differentiation neuromodulator role in neurodevelopment.

Authors:  J M Muller; V Lelievre; L Becq-Giraudon; A C Meunier
Journal:  Mol Neurobiol       Date:  1995 Apr-Jun       Impact factor: 5.590

7.  Vasoactive intestinal peptide enhances its own expression in sympathetic neurons after injury.

Authors:  R P Mohney; R E Zigmond
Journal:  J Neurosci       Date:  1998-07-15       Impact factor: 6.167

Review 8.  International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide.

Authors:  A J Harmar; A Arimura; I Gozes; L Journot; M Laburthe; J R Pisegna; S R Rawlings; P Robberecht; S I Said; S P Sreedharan; S A Wank; J A Waschek
Journal:  Pharmacol Rev       Date:  1998-06       Impact factor: 25.468

9.  A vasoactive intestinal peptide antagonist inhibits the growth of glioblastoma cells.

Authors:  A Sharma; J Walters; Y Gozes; M Fridkin; D Brenneman; I Gozes; T W Moody
Journal:  J Mol Neurosci       Date:  2001-12       Impact factor: 3.444
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.