Literature DB >> 8249240

Relationship between pharmacological properties and clinical efficacy of ruminant anthelmintics.

C E Lanusse1, R K Prichard.   

Abstract

The purpose of this review article is to establish a relationship between pharmacological properties and clinical efficacy of the most widely used broad-spectrum veterinary anthelmintics. The impact of drug pharmacokinetics/pharmacodynamics on anthelmintic efficacy and resistance is discussed. We review the clinical pharmacokinetics of the currently available anthelmintics used in livestock-imidazothiazoles, tetrahydropyrimidines, benzimidazoles/pro-benzimidazoles, salicylanilides (closantel) and avermectin-type compounds. Understanding the pharmacokinetic and metabolic behaviour of broad-spectrum anthelmintics in the host, and factors modulating that behaviour, is highly important for maximizing anthelmintic utility and efficacy.

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Year:  1993        PMID： 8249240     DOI： 10.1016/0304-4017(93)90115-4

Source DB:  PubMed          Journal:  Vet Parasitol        ISSN： 0304-4017            Impact factor:   2.738


  13 in total

1.  Ivermectin in senegalese peulh sheep: influence of sex on plasma disposition.

Authors:  T Bengone Ndong; Y Kane; E H M Diouf; M Alvinerie
Journal:  Vet Res Commun       Date:  2007-01-27       Impact factor: 2.459

2.  Comparative pharmacokinetics of ivermectin alone and a novel formulation of ivermectin and rafoxanide in calves and sheep.

Authors:  H A El-Banna; A Goudah; H El-Zorba; S Abd-El-Rahman
Journal:  Parasitol Res       Date:  2008-02-23       Impact factor: 2.289

3.  Eprinomectin in dairy zebu Gobra cattle (Bos indicus): plasma kinetics and excretion in milk.

Authors:  T Bengone-Ndong; M A Ba; Y Kane; I Sané; J F Sutra; M Alvinerie
Journal:  Parasitol Res       Date:  2006-01-14       Impact factor: 2.289

4.  Pharmacokinetics of ricobendazole after its intravenous, intraruminal and subcutaneous administration in sheep.

Authors:  E A Formentini; N Mestorino; J O Errecalde
Journal:  Vet Res Commun       Date:  2005-10       Impact factor: 2.459

5.  Enhanced plasma availability of the metabolites of albendazole in fasted adult sheep.

Authors:  A Lifschitz; G Virkel; M Mastromarino; C Lanusse
Journal:  Vet Res Commun       Date:  1997-04       Impact factor: 2.459

6.  Plasma disposition and faecal excretion of netobimin metabolites and enantiospecific disposition of albendazole sulphoxide produced in ewes.

Authors:  C Gokbulut; V Y Cirak; B Senlik
Journal:  Vet Res Commun       Date:  2006-10       Impact factor: 2.459

7.  A questionnaire survey on the practices adopted to control gastrointestinal nematode parasitism in dairy goat farms in France.

Authors:  H Hoste; C Chartier; E Etter; C Goudeau; F Soubirac; Y Lefrileux
Journal:  Vet Res Commun       Date:  2000-11       Impact factor: 2.459

8.  Assessment of Diet-Related Changes on Albendazole Absorption, Systemic Exposure, and Pattern of Urinary Excretion in Treated Human Volunteers.

Authors:  L Ceballos; E Nieves; M Juárez; R Aveldaño; M Travacio; J Martos; R Cimino; J L Walson; A Krolewiecki; C Lanusse; L Alvarez
Journal:  Antimicrob Agents Chemother       Date:  2021-08-17       Impact factor: 5.191

9.  Phenotypic and genotypic analysis of benzimidazole resistance in the ovine parasite Nematodirus battus.

Authors:  Alison A Morrison; Sian Mitchell; Rebecca Mearns; Iain Richards; Jacqui B Matthews; David J Bartley
Journal:  Vet Res       Date:  2014-12-09       Impact factor: 3.683

10.  Genetic variations in the beta-tubulin gene and the internal transcribed spacer 2 region of Trichuris species from man and baboons.

Authors:  Tina V A Hansen; Stig M Thamsborg; Annette Olsen; Roger K Prichard; Peter Nejsum
Journal:  Parasit Vectors       Date:  2013-08-12       Impact factor: 3.876
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