Literature DB >> 8243938

[Fatal fulminant hepatitis induced by nilutamide (Anandron)].

P Pescatore1, P Hammel, F Durand, P Bertheau, J Bernuau, D Huc, J L Gerbal, C Degott, J P Benhamou.   

Abstract

The first case of fatal fulminant hepatitis probably caused by nilutamide, a non steroidal antiandrogen derivative, is reported. Nilutamide administration had been continued for 6 days after the occurrence of jaundice, 52 days after beginning of treatment. The rapidly fatal outcome might have been promoted by coadministration of phenobarbital.

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Year:  1993        PMID: 8243938

Source DB:  PubMed          Journal:  Gastroenterol Clin Biol        ISSN: 0399-8320


  2 in total

1.  Fulminant hepatic failure due to nilutamide hepatotoxicity.

Authors:  Shehzad N Merwat; Wareef Kabbani; Douglas G Adler
Journal:  Dig Dis Sci       Date:  2008-08-08       Impact factor: 3.199

2.  Drug-related hepatotoxicity and hepatic failure following combined androgen blockade.

Authors:  Inmaculada Castro Beza; Jesús Sánchez Ruiz; Francisco José Peracaula Espino; M Isabel Villanego Beltrán
Journal:  Clin Transl Oncol       Date:  2008-09       Impact factor: 3.405

  2 in total

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