Literature DB >> 18688719

Fulminant hepatic failure due to nilutamide hepatotoxicity.

Shehzad N Merwat1, Wareef Kabbani, Douglas G Adler.   

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Year:  2008        PMID: 18688719     DOI: 10.1007/s10620-008-0406-8

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


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  16 in total

1.  Tolerability of Nonsteroidal Antiandrogens in the Treatment of Advanced Prostate Cancer.

Authors: 
Journal:  Oncologist       Date:  1997

2.  Fatal and nonfatal hepatotoxicity associated with flutamide.

Authors:  D K Wysowski; J P Freiman; J B Tourtelot; M L Horton
Journal:  Ann Intern Med       Date:  1993-06-01       Impact factor: 25.391

3.  Inhibition by nilutamide of the mitochondrial respiratory chain and ATP formation. Possible contribution to the adverse effects of this antiandrogen.

Authors:  A Berson; L Schmets; C Fisch; D Fau; C Wolf; B Fromenty; D Deschamps; D Pessayre
Journal:  J Pharmacol Exp Ther       Date:  1994-07       Impact factor: 4.030

4.  Efficacy of the combination of nilutamide plus orchidectomy in patients with metastatic prostatic cancer. A meta-analysis of seven randomized double-blind trials (1056 patients).

Authors:  C Bertagna; A De Géry; M Hucher; J P François; J Zanirato
Journal:  Br J Urol       Date:  1994-04

5.  Anandron (RU 23908) in metastatic prostate cancer: preliminary results of a multicentric Italian study.

Authors:  F Boccardo; A U Decensi; D Guarneri; G Martorana; L Fioretto; E Mini; M P Macaluso; L Giuliani; L Santi; P Periti
Journal:  Cancer Detect Prev       Date:  1991

6.  Mechanism for the hepatotoxicity of the antiandrogen, nilutamide. Evidence suggesting that redox cycling of this nitroaromatic drug leads to oxidative stress in isolated hepatocytes.

Authors:  D Fau; A Berson; D Eugene; B Fromenty; C Fisch; D Pessayre
Journal:  J Pharmacol Exp Ther       Date:  1992-10       Impact factor: 4.030

7.  Monotherapy with nilutamide, a pure nonsteroidal antiandrogen, in untreated patients with metastatic carcinoma of the prostate. The Italian Prostatic Cancer Project.

Authors:  A U Decensi; F Boccardo; D Guarneri; N Positano; M C Paoletti; M Costantini; G Martorana; L Giuliani
Journal:  J Urol       Date:  1991-08       Impact factor: 7.450

Review 8.  Advances and trends in hormonal therapy for advanced prostate cancer.

Authors:  F M Debruyne; G A Dijkman
Journal:  Eur Urol       Date:  1995       Impact factor: 20.096

9.  Orchiectomy and nilutamide or placebo as treatment of metastatic prostatic cancer in a multinational double-blind randomized trial.

Authors:  R A Janknegt; C C Abbou; R Bartoletti; L Bernstein-Hahn; B Bracken; J M Brisset; F C Da Silva; G Chisholm; E D Crawford; F M Debruyne
Journal:  J Urol       Date:  1993-01       Impact factor: 7.450

10.  [Fatal fulminant hepatitis induced by nilutamide (Anandron)].

Authors:  P Pescatore; P Hammel; F Durand; P Bertheau; J Bernuau; D Huc; J L Gerbal; C Degott; J P Benhamou
Journal:  Gastroenterol Clin Biol       Date:  1993
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