| Literature DB >> 8237794 |
M F Boeniger1, L K Lowry, J Rosenberg.
Abstract
This paper reviews the process of elimination of creatinine (CRE), and the limitations presented when using it to express urine concentrations. This literature review leads to three conclusions: (1) CRE excretion is subject to wide fluctuations due to specific internal and external factors; (2) the use of CRE to correct chemical concentrations in urine will not necessarily improve the correlation to the exposure dose for all chemicals (it may, in fact, worsen the result); and (3) other means of expressing urine concentration may offer greater accuracy towards estimating individually absorbed dose.Entities:
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Year: 1993 PMID： 8237794 DOI： 10.1080/15298669391355134
Source DB: PubMed Journal: Am Ind Hyg Assoc J ISSN： 0002-8894