Literature DB >> 8234490

The tet(K) gene of plasmid pT181 of Staphylococcus aureus encodes an efflux protein that contains 14 transmembrane helices.

G G Guay1, S A Khan, D M Rothstein.   

Abstract

The corrected DNA sequence of the tet(K) structural gene, encoding the tetracycline efflux protein from Staphylococcus aureus, is reported. The Tet(K) protein is homologous to related tetracycline efflux proteins throughout the protein, including at the C-terminal end. Hydropathy plotting now clearly indicates that the Tet(K) protein contains 14 transmembrane alpha-helices.

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Year:  1993        PMID： 8234490     DOI： 10.1006/plas.1993.1045

Source DB:  PubMed          Journal:  Plasmid        ISSN： 0147-619X            Impact factor:   3.466


  17 in total

1.  The TetA(K) tetracycline/H(+) antiporter from Staphylococcus aureus: mutagenesis and functional analysis of motif C.

Authors:  S L Ginn; M H Brown; R A Skurray
Journal:  J Bacteriol       Date:  2000-03       Impact factor: 3.490

2.  An IS257-derived hybrid promoter directs transcription of a tetA(K) tetracycline resistance gene in the Staphylococcus aureus chromosomal mec region.

Authors:  A E Simpson; R A Skurray; N Firth
Journal:  J Bacteriol       Date:  2000-06       Impact factor: 3.490

3.  Detection of a common and persistent tet(L)-carrying plasmid in chicken-waste-impacted farm soil.

Authors:  Yaqi You; Markus Hilpert; Mandy J Ward
Journal:  Appl Environ Microbiol       Date:  2012-03-02       Impact factor: 4.792

4.  Membrane topology of the metal-tetracycline/H+ antiporter TetA(K) from Staphylococcus aureus.

Authors:  S L Ginn; M H Brown; R A Skurray
Journal:  J Bacteriol       Date:  1997-06       Impact factor: 3.490

5.  Expanding the Spectrum of Antibiotics Capable of Killing Multidrug-Resistant Staphylococcus aureus and Pseudomonas aeruginosa.

Authors:  Anh K Lam; Hannah Panlilio; Jennifer Pusavat; Cassandra L Wouters; Erika L Moen; Robert E Brennan; Charles V Rice
Journal:  ChemMedChem       Date:  2020-06-26       Impact factor: 3.466

6.  Replication of staphylococcal multiresistance plasmids.

Authors:  N Firth; S Apisiridej; T Berg; B A O'Rourke; S Curnock; K G Dyke; R A Skurray
Journal:  J Bacteriol       Date:  2000-04       Impact factor: 3.490

7.  Role of Enterococcus faecalis surface protein Esp in the pathogenesis of ascending urinary tract infection.

Authors:  N Shankar; C V Lockatell; A S Baghdayan; C Drachenberg; M S Gilmore; D E Johnson
Journal:  Infect Immun       Date:  2001-07       Impact factor: 3.441

8.  Staphylococcus aureus Tet38 Efflux Pump Structural Modeling and Roles of Essential Residues in Drug Efflux and Host Cell Internalization.

Authors:  Q C Truong-Bolduc; Y Wang; D C Hooper
Journal:  Infect Immun       Date:  2021-04-16       Impact factor: 3.441

Review 9.  Mobile genetic elements of Staphylococcus aureus.

Authors:  Natalia Malachowa; Frank R DeLeo
Journal:  Cell Mol Life Sci       Date:  2010-07-29       Impact factor: 9.261

10.  StaphPlex system for rapid and simultaneous identification of antibiotic resistance determinants and Panton-Valentine leukocidin detection of staphylococci from positive blood cultures.

Authors:  Yi-Wei Tang; Abdullah Kilic; Qunying Yang; Sigrid K McAllister; Haijing Li; Rebecca S Miller; Melinda McCormac; Karen D Tracy; Charles W Stratton; Jian Han; Brandi Limbago
Journal:  J Clin Microbiol       Date:  2007-04-19       Impact factor: 5.948
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