Literature DB >> 8232984

The potential for increasing seizure frequency, relapse, and appearance of new seizure types with vigabatrin.

A Lortie1, C Chiron, J Mumford, O Dulac.   

Abstract

Although generally effective, various antiepileptic drugs have been reported on occasion to increase seizure frequency, result in seizure relapse, or elicit new types of seizures. Some seizure types and epilepsy syndromes appear more prone than others to exacerbation by a given drug. Vigabatrin is rarely associated with seizure worsening, and then mainly in patients with resistant generalized epilepsies.

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Year:  1993        PMID: 8232984

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  14 in total

Review 1.  Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin.

Authors:  O A Petroff; D L Rothman
Journal:  Mol Neurobiol       Date:  1998-02       Impact factor: 5.590

2.  Diagnosing idiopathic/cryptogenic epilepsy syndromes in infancy.

Authors:  N Sarisjulis; B Gamboni; P Plouin; A Kaminska; O Dulac
Journal:  Arch Dis Child       Date:  2000-03       Impact factor: 3.791

Review 3.  A comparative review of the adverse effects of anticonvulsants in children with epilepsy.

Authors:  S J Wallace
Journal:  Drug Saf       Date:  1996-12       Impact factor: 5.606

Review 4.  Safety and tolerability of antiepileptic drug treatment in children with epilepsy.

Authors:  Renzo Guerrini; Gaetano Zaccara; Giancarlo la Marca; Anna Rosati
Journal:  Drug Saf       Date:  2012-07-01       Impact factor: 5.606

Review 5.  Diagnosis and treatment of epilepsy in children and adolescents.

Authors:  L D Morton; J M Pellock
Journal:  Drugs       Date:  1996-03       Impact factor: 9.546

Review 6.  Adverse reactions to new anticonvulsant drugs.

Authors:  I C Wong; S D Lhatoo
Journal:  Drug Saf       Date:  2000-07       Impact factor: 5.606

Review 7.  Valproate as a mainstay of therapy for pediatric epilepsy.

Authors:  Renzo Guerrini
Journal:  Paediatr Drugs       Date:  2006       Impact factor: 3.022

Review 8.  Lamotrigine. A review of its use in childhood epilepsy.

Authors:  C R Culy; K L Goa
Journal:  Paediatr Drugs       Date:  2000 Jul-Aug       Impact factor: 3.022

9.  Seizures in a boy with succinic semialdehyde dehydrogenase deficiency treated with vigabatrin (gamma-vinyl-GABA).

Authors:  D Matern; W Lehnert; K M Gibson; R Korinthenberg
Journal:  J Inherit Metab Dis       Date:  1996       Impact factor: 4.982

10.  Astrocytic GABA transporter GAT-1 dysfunction in experimental absence seizures.

Authors:  Tiina Pirttimaki; H Rheinallt Parri; Vincenzo Crunelli
Journal:  J Physiol       Date:  2012-10-22       Impact factor: 5.182

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