| Literature DB >> 8232783 |
J S Vles1, A M van der Heyden, A Ghijs, J Troost.
Abstract
The anti-epileptic effect of vigabatrin as a first choice therapy was investigated in 6 children suffering from infantile spasms (IS). All 6 children showed a reduction in seizure frequency. Three children became seizure-free within a period of 2 weeks. Because our results suggest "an all or nothing phenomenon", a period of 2 weeks may be sufficient to evaluate the efficacy of vigabatrin in untreated infants suffering from IS. We suggest to use vigabatrin as a first choice anti-epileptic drug in infants with IS.Entities:
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Year: 1993 PMID： 8232783 DOI： 10.1055/s-2008-1071546
Source DB: PubMed Journal: Neuropediatrics ISSN： 0174-304X Impact factor: 1.947