Literature DB >> 8230488

Interconnection between thyroid hormone signalling pathways and parvovirus cytotoxic functions.

J M Vanacker1, V Laudet, G Adelmant, D Stéhelin, J Rommelaere.   

Abstract

Nonstructural (NS) proteins of autonomous parvoviruses can repress expression driven by heterologous promoters, an activity which thus far has not been separated from their cytotoxic effects. It is shown here that, in transient transfection assays, the NS-1 protein of the parvovirus minute virus of mice (MVMp) activates the promoter of the human c-erbA1 gene, encoding the thyroid hormone (T3) receptor alpha. The endogenous c-erbA1 promoter is also a target for induction upon MVMp infection. Moreover, T3 was found to up-modulate the level of cell sensitivity to parvovirus attack. These data suggest an interconnection between T3 signalling and NS cytotoxic pathways.

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Year:  1993        PMID： 8230488      PMCID： PMC238238     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  28 in total

1.  CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements.

Authors:  B Luckow; G Schütz
Journal:  Nucleic Acids Res       Date:  1987-07-10       Impact factor: 16.971

2.  Thyroid hormone receptor alpha isoforms generated by alternative splicing differentially activate myosin HC gene transcription.

Authors:  S Izumo; V Mahdavi
Journal:  Nature       Date:  1988-08-11       Impact factor: 49.962

Review 3.  The autonomously replicating parvoviruses of vertebrates.

Authors:  S F Cotmore; P Tattersall
Journal:  Adv Virus Res       Date:  1987       Impact factor: 9.937

4.  High-efficiency transformation of mammalian cells by plasmid DNA.

Authors:  C Chen; H Okayama
Journal:  Mol Cell Biol       Date:  1987-08       Impact factor: 4.272

5.  The c-erb-A protein is a high-affinity receptor for thyroid hormone.

Authors:  J Sap; A Muñoz; K Damm; Y Goldberg; J Ghysdael; A Leutz; H Beug; B Vennström
Journal:  Nature       Date:  1986 Dec 18-31       Impact factor: 49.962

6.  The c-erb-A gene encodes a thyroid hormone receptor.

Authors:  C Weinberger; C C Thompson; E S Ong; R Lebo; D J Gruol; R M Evans
Journal:  Nature       Date:  1986 Dec 18-31       Impact factor: 49.962

7.  Characterization of the trans-activation-responsive element of the parvovirus H-1 P38 promoter.

Authors:  S L Rhode; S M Richard
Journal:  J Virol       Date:  1987-09       Impact factor: 5.103

8.  Terminal regions of the NS-1 protein of the parvovirus minute virus of mice are involved in cytotoxicity and promoter trans inhibition.

Authors:  D Legendre; J Rommelaere
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

9.  Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

Authors:  J D Dignam; R M Lebovitz; R G Roeder
Journal:  Nucleic Acids Res       Date:  1983-03-11       Impact factor: 16.971

10.  Transformation of human fibroblasts by ionizing radiation, a chemical carcinogen, or simian virus 40 correlates with an increase in susceptibility to the autonomous parvoviruses H-1 virus and minute virus of mice.

Authors:  J J Cornelis; P Becquart; N Duponchel; N Salomé; B L Avalosse; M Namba; J Rommelaere
Journal:  J Virol       Date:  1988-05       Impact factor: 5.103
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  11 in total

1.  Modulation of minute virus of mice cytotoxic activities through site-directed mutagenesis within the NS coding region.

Authors:  Laurent Daeffler; Rita Hörlein; Jean Rommelaere; Jürg P F Nüesch
Journal:  J Virol       Date:  2003-12       Impact factor: 5.103

2.  Transactivation of a cellular promoter by the NS1 protein of the parvovirus minute virus of mice through a putative hormone-responsive element.

Authors:  J M Vanacker; R Corbau; G Adelmant; M Perros; V Laudet; J Rommelaere
Journal:  J Virol       Date:  1996-04       Impact factor: 5.103

3.  The cytotoxicity of the parvovirus minute virus of mice nonstructural protein NS1 is related to changes in the synthesis and phosphorylation of cell proteins.

Authors:  F Anouja; R Wattiez; S Mousset; P Caillet-Fauquet
Journal:  J Virol       Date:  1997-06       Impact factor: 5.103

4.  Upstream CREs participate in the basal activity of minute virus of mice promoter P4 and in its stimulation in ras-transformed cells.

Authors:  M Perros; L Deleu; J M Vanacker; Z Kherrouche; N Spruyt; S Faisst; J Rommelaere
Journal:  J Virol       Date:  1995-09       Impact factor: 5.103

5.  ras oncogene-dependent activation of the P4 promoter of minute virus of mice through a proximal P4 element interacting with the Ets family of transcription factors.

Authors:  F Fuks; L Deleu; C Dinsart; J Rommelaere; S Faisst
Journal:  J Virol       Date:  1996-03       Impact factor: 5.103

6.  Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.

Authors:  Sunil K Tewary; Lingfei Liang; Zihan Lin; Annie Lynn; Susan F Cotmore; Peter Tattersall; Haiyan Zhao; Liang Tang
Journal:  Virology       Date:  2014-12-18       Impact factor: 3.616

7.  Targeting of promoters for trans activation by a carboxy-terminal domain of the NS-1 protein of the parvovirus minute virus of mice.

Authors:  D Legendre; J Rommelaere
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

8.  Non-structural proteins of Periplaneta fuliginosa densovirus inhibit cellular gene expression and induce necrosis in Sf9 cell cultures.

Authors:  Bo Yang; Dawei Cai; Peiran Yu; Xiaomin Dong; Zhigang Liu; Zheng Hu; Xu Cao; Jiamin Zhang; Yuanyang Hu
Journal:  Virus Genes       Date:  2009-03-18       Impact factor: 2.332

9.  The NS1 polypeptide of the murine parvovirus minute virus of mice binds to DNA sequences containing the motif [ACCA]2-3.

Authors:  S F Cotmore; J Christensen; J P Nüesch; P Tattersall
Journal:  J Virol       Date:  1995-03       Impact factor: 5.103

10.  NF-Y controls transcription of the minute virus of mice P4 promoter through interaction with an unusual binding site.

Authors:  Z Gu; S Plaza; M Perros; C Cziepluch; J Rommelaere; J J Cornelis
Journal:  J Virol       Date:  1995-01       Impact factor: 5.103
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