| Literature DB >> 8224914 |
Y H Kim1, H Y Yoo, G Jung, J Y Kim, H M Rho.
Abstract
A rat genomic DNA (SOD1) encoding Cu/Zn superoxide dismutase (SOD1) (superoxide; superoxide oxidoreductase, EC 1.15.1.1) was cloned and sequenced. The rat SOD1 gene consisted of five exons and four introns spanning about 6 kb. The transcription start point (tsp) was observed 93 bp upstream from the ATG codon by primer extension analysis. The 5'-flanking sequence of SOD1 contained two CCAAT box motifs, a TATA box and four GC-like boxes. In the 3'-flanking region of SOD1, a polyadenylation signal, consensus sequence YGTGTTYY, and a G/T cluster were observed. A rat identifier (ID) sequence, a repetitive element of the rat genome, was located at between 569 and 484 bp upstream from the tsp.Entities:
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Year: 1993 PMID： 8224914 DOI： 10.1016/0378-1119(93)90650-r
Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688