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Literature DB >> 8221937

Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae.

Y O Chernoff¹, I L Derkach, S G Inge-Vechtomov.

Abstract

Previously, we have shown that plasmid-mediated multiplication of Saccharomyces cerevisiae wild-type SUP35 gene leads to omnipotent suppression and is incompatible with psi-factor, which is an endogenous extrachromosomal suppressor. Here, we describe a frequent de-novo appearance of psi-like factors in mitotic progeny of yeast transformants containing multicopy SUP35 gene.

Entities: Disease Gene Species

Mesh：

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Year: 1993 PMID： 8221937 DOI： 10.1007/bf00351802

Source DB: PubMed Journal: Curr Genet ISSN： 0172-8083 Impact factor: 3.886

8 in total

1. A non-Mendelian factor, [eta(+)], causes lethality of yeast omnipotent-suppressor strains.

Authors: S W Liebman; J A All-Robyn
Journal: Curr Genet Date: 1984-10 Impact factor: 3.886

Review 2. The psi factor of yeast: a problem in inheritance.

Authors: B S Cox; M F Tuite; C S McLaughlin
Journal: Yeast Date: 1988-09 Impact factor: 3.239

3. Isolation of omnipotent suppressors in an [eta+] yeast strain.

Authors: J A All-Robyn; D Kelley-Geraghty; E Griffin; N Brown; S W Liebman
Journal: Genetics Date: 1990-03 Impact factor: 4.562

4. Transformation of psi- Saccharomyces cerevisiae to psi+ with DNA co-purified with 3 micron circles.

Authors: H Dai; S H Tsay; P M Lund; B S Cox
Journal: Curr Genet Date: 1986 Impact factor: 3.886

5. Replication and recombination functions associated with the yeast plasmid, 2 mu circle.

Authors: J R Broach; J B Hicks
Journal: Cell Date: 1980-09 Impact factor: 41.582

6. Nucleotide sequence of the SUP2 (SUP35) gene of Saccharomyces cerevisiae.

Authors: V V Kushnirov; M D Ter-Avanesyan; M V Telckov; A P Surguchov; V N Smirnov; S G Inge-Vechtomov
Journal: Gene Date: 1988-06-15 Impact factor: 3.688

7. Dosage-dependent translational suppression in yeast Saccharomyces cerevisiae.

Authors: Y O Chernoff; S G Inge-Vechtomov; I L Derkach; M V Ptyushkina; O V Tarunina; A R Dagkesamanskaya; M D Ter-Avanesyan
Journal: Yeast Date: 1992-07 Impact factor: 3.239

8. Agents that cause a high frequency of genetic change from [psi+] to [psi-] in Saccharomyces cerevisiae.

Authors: M F Tuite; C R Mundy; B S Cox
Journal: Genetics Date: 1981-08 Impact factor: 4.562

8 in total

130 in total

1. Evidence for a protein mutator in yeast: role of the Hsp70-related chaperone ssb in formation, stability, and toxicity of the [PSI] prion.

Authors: Y O Chernoff; G P Newnam; J Kumar; K Allen; A D Zink
Journal: Mol Cell Biol Date: 1999-12 Impact factor: 4.272

Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae.

1. A non-Mendelian factor, [eta(+)], causes lethality of yeast omnipotent-suppressor strains.

Review 2. The psi factor of yeast: a problem in inheritance.

3. Isolation of omnipotent suppressors in an [eta+] yeast strain.

4. Transformation of psi- Saccharomyces cerevisiae to psi+ with DNA co-purified with 3 micron circles.

5. Replication and recombination functions associated with the yeast plasmid, 2 mu circle.

6. Nucleotide sequence of the SUP2 (SUP35) gene of Saccharomyces cerevisiae.

7. Dosage-dependent translational suppression in yeast Saccharomyces cerevisiae.

8. Agents that cause a high frequency of genetic change from [psi+] to [psi-] in Saccharomyces cerevisiae.

1. Evidence for a protein mutator in yeast: role of the Hsp70-related chaperone ssb in formation, stability, and toxicity of the [PSI] prion.

2. Dependence and independence of [PSI(+)] and [PIN(+)]: a two-prion system in yeast?

3. Strains of [PSI(+)] are distinguished by their efficiencies of prion-mediated conformational conversion.

4. The role of Sis1 in the maintenance of the [RNQ+] prion.

5. The [KIL-d] element specifically regulates viral gene expression in yeast.

6. Prion properties of the Sup35 protein of yeast Pichia methanolica.

7. A prion of yeast metacaspase homolog (Mca1p) detected by a genetic screen.

8. Organizing biochemistry in space and time using prion-like self-assembly.

9. The NatA acetyltransferase couples Sup35 prion complexes to the [PSI+] phenotype.

10. The [URE3] prion is an aggregated form of Ure2p that can be cured by overexpression of Ure2p fragments.