Literature DB >> 8220975

The 62 MeV proton beam for the treatment of ocular melanoma at Clatterbridge.

D E Bonnett1, A Kacperek, M A Sheen, R Goodall, T E Saxton.   

Abstract

A second treatment room and beam line has been constructed at the Cyclotron Unit at Clatterbridge for the purpose of using 62 MeV protons for the treatment of ocular melanoma. A uniform beam is produced by a double foil scattering system. The initial Bragg peak is spread across the target volume by the use of beam modulators. These are rotating four-vaned stepped absorbers made from Perspex. Two beam lines can be configured with different positions of modulators and range limiters. The first has a maximum penetration of 31.9 +/- 0.2 mm in water and the second a penetration of 31.2 +/- 0.2 mm. The second configuration has the advantage of less variation in beam penumbra, with a typical value of 1.7 +/- 0.1 mm for the 90% to 10% decrement lines. The patients are treated with individually shaped collimators. Beam output varies by less than 2% over the range of collimator areas used. The resulting whole-body dose equivalent to patient has also been assessed. In the first three years of operation over 250 patients have been treated.

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Year:  1993        PMID: 8220975     DOI: 10.1259/0007-1285-66-790-907

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  5 in total

1.  Proton tracking for medical imaging and dosimetry.

Authors:  J T Taylor; P P Allport; G L Casse; N A Smith; I Tsurin; N M Allinson; M Esposito; A Kacperek; J Nieto-Camero; T Price; C Waltham
Journal:  J Instrum       Date:  2015-02-10       Impact factor: 1.415

2.  Proton therapy for uveal melanomas and other eye lesions.

Authors:  J E Munzenrider
Journal:  Strahlenther Onkol       Date:  1999-06       Impact factor: 3.621

3.  Reduction of the secondary neutron dose in passively scattered proton radiotherapy, using an optimized pre-collimator/collimator.

Authors:  David J Brenner; Carl D Elliston; Eric J Hall; Harald Paganetti
Journal:  Phys Med Biol       Date:  2009-09-24       Impact factor: 3.609

4.  Secondary neutron dose measurement for proton eye treatment using an eye snout with a borated neutron absorber.

Authors:  Dong Wook Kim; Weon Kuu Chung; Jungwook Shin; Young Kyung Lim; Dongho Shin; Se Byeong Lee; Myongguen Yoon; Sung-Yong Park; Dong Oh Shin; Jung Keun Cho
Journal:  Radiat Oncol       Date:  2013-07-17       Impact factor: 3.481

5.  A new silicon tracker for proton imaging and dosimetry.

Authors:  J T Taylor; C Waltham; T Price; N M Allinson; P P Allport; G L Casse; A Kacperek; S Manger; N A Smith; I Tsurin
Journal:  Nucl Instrum Methods Phys Res A       Date:  2016-09-21       Impact factor: 1.455

  5 in total

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