Literature DB >> 821775

Effects of long-term feeding of glibenclamide on normal rats.

A V George, K T Augusti.   

Abstract

Prolonged administration of glibenclamide decreased blood sugar, liver glycogen and protein and increased liver and serum lipids and organic phosphates of liver in normal rats. A significant weight increase observed in glibenclamide group of rats is attributed to lipid accumulation.

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Year:  1976        PMID： 821775     DOI： 10.1007/BF02003721

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  28 in total

1.  MECHANISM OF ACTION OF ORAL ANTIDIABETIC DRUGS: POTENTIATION OF PLASMA EFFECT AND INSULIN EFFECT ON GLUCOSE UPTAKE OF THE RAT DIAPHRAGM.

Authors:  M B BHIDE; R AIMAN
Journal:  Indian J Med Res       Date:  1963-07       Impact factor: 2.375

2.  Oral hypoglycaemic agents in the treatment of diabetes mellitus.

Authors:  A LOUBATIERES
Journal:  Proc R Soc Med       Date:  1960-08

3.  The determination of glycogen in liver and muscle by use of anthrone reagent.

Authors:  N V CARROLL; R W LONGLEY; J H ROE
Journal:  J Biol Chem       Date:  1956-06       Impact factor: 5.157

4.  Notes on sugar determination.

Authors:  M SMOGYI
Journal:  J Biol Chem       Date:  1952-03       Impact factor: 5.157

5.  Mechanism of action of antilipolytic agents: comparison of the effects of insulin, tolbutamide, and phenformin on lipolysis induced by dibutyryl cyclic AMP plus theophylline.

Authors:  J D Brown; D B Stone; A A Steele
Journal:  Metabolism       Date:  1969-11       Impact factor: 8.694

6.  Mode of action of oral hypoglycaemic agents. I. Effect of tolbutamide on some glycolytic enzymes.

Authors:  K T Augusti; P A Kurup
Journal:  Indian J Biochem       Date:  1967-06

7.  Effect of long term administration of tolbutamide and phenformin on the aortic glycosaminoglycans in normal rats.

Authors:  K Prasannan; P A Kurup
Journal:  Indian J Biochem Biophys       Date:  1973-03       Impact factor: 1.918

Review 8.  Appraisal of the extrapancreatic actions of sulfonylureas.

Authors:  J M Feldman; H E Lebovitz
Journal:  Arch Intern Med       Date:  1969-03

9.  Effects of long-term feeding of tolbutamide and phenformin on normal rats.

Authors:  K Prasannan; K T Augusti
Journal:  Indian J Med Res       Date:  1973-07       Impact factor: 2.375

10.  Effect of in vivo administration of various oral hypoglycemic agents on hepatic protein synthesis.

Authors:  L R DeChatelet; H J McDonald
Journal:  Proc Soc Exp Biol Med       Date:  1968-02
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  1 in total

1.  Studies on the biochemical effects of glibenclamide on alloxan diabetic rabbits.

Authors:  P T Annamala; K T Augusti
Journal:  Experientia       Date:  1980-04-15
  1 in total

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