| Literature DB >> 6769691 |
Abstract
Treatment of alloxan diabetic rabbits with glibenclamide, the most potent of the sulfonylureas, for a period of 2 months, significantly ameliorated the diabetic condition. It produced a decrease in serum and liver lipids, amino acids, serum urea, blood sugar and urine sugar; increase in body weight, serum and liver proteins, liver glycogen, glucose tolerance and serum and liver acid labile phosphates. The possible mechanism of action of this hypoglycemic agent is discussed.Entities:
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Year: 1980 PMID： 6769691 DOI： 10.1007/bf01975099
Source DB: PubMed Journal: Experientia ISSN： 0014-4754