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Literature DB >> 8213124

Chondrocyte behavior in fibrin glue in vitro.

G N Homminga¹, P Buma, H W Koot, P M van der Kraan, W B van den Berg.

Abstract

To test fibrin glue as a vehicle in chondrocyte transplantation, chondrocytes, isolated from articular cartilage of young rabbits, were mixed with Tissucol, a highly concentrated fibrin glue, and cultured for 7 days. Histology, autoradiography (35-S) and electron microscopy were used to study chondrocyte behavior and phenotypic expression. Chondrocytes multiplied, retained their morphology, and produced matrix in fibrin glue as long as the cells were surrounded by the glue. Glue disintegration started after 3 days and was accelerated by higher cell concentrations.

Entities: Disease Species

Mesh：

Substances：
Fibrin Tissue Adhesive

Year: 1993 PMID： 8213124 DOI： 10.3109/17453679308993663

Source DB: PubMed Journal: Acta Orthop Scand ISSN： 0001-6470

Keyword Cloud
Cited

23 in total

1. Crosslinkable hydrogels derived from cartilage, meniscus, and tendon tissue.

Authors: Jetze Visser; Peter A Levett; Nikae C R te Moller; Jeremy Besems; Kristel W M Boere; Mattie H P van Rijen; Janny C de Grauw; Wouter J A Dhert; P René van Weeren; Jos Malda
Journal: Tissue Eng Part A Date: 2015-02-09 Impact factor: 3.845

2. Next Generation Mesenchymal Stem Cell (MSC)-Based Cartilage Repair Using Scaffold-Free Tissue Engineered Constructs Generated with Synovial Mesenchymal Stem Cells.

Authors: Kazunori Shimomura; Wataru Ando; Yu Moriguchi; Norihiko Sugita; Yukihiko Yasui; Kota Koizumi; Hiromichi Fujie; David A Hart; Hideki Yoshikawa; Norimasa Nakamura
Journal: Cartilage Date: 2015-03-24 Impact factor: 4.634

Review 3. Scaffold-free, stem cell-based cartilage repair.

Authors: Yukihiko Yasui; Wataru Ando; Kazunori Shimomura; Kota Koizumi; Chijimatsu Ryota; Shuichi Hamamoto; Masato Kobayashi; Hideki Yoshikawa; Norimasa Nakamura
Journal: J Clin Orthop Trauma Date: 2016-06-28

4. Repair of Osteochondral Defects in Rabbit Knee Using Menstrual Blood Stem Cells Encapsulated in Fibrin Glue: A Good Stem Cell Candidate for the Treatment of Osteochondral Defects.

Authors: Manijeh Khanmohammadi; Hannaneh Golshahi; Zahra Saffarian; Samaneh Montazeri; Somaye Khorasani; Somaieh Kazemnejad
Journal: Tissue Eng Regen Med Date: 2019-04-27 Impact factor: 4.169

5. Culture of chondrocytes in alginate surrounded by fibrin gel: characteristics of the cells over a period of eight weeks.

Authors: K F Almqvist; L Wang; J Wang; D Baeten; M Cornelissen; R Verdonk; E M Veys; G Verbruggen
Journal: Ann Rheum Dis Date: 2001-08 Impact factor: 19.103

10. Effect of dynamic compressive loading and its combination with a growth factor on the chondrocytic phenotype of 3-dimensional scaffold-embedded chondrocytes.

Authors: Kosei Ando; Shinji Imai; Eiji Isoya; Mitsuhiko Kubo; Tomohiro Mimura; Suguru Shioji; Hisao Ueyama; Yoshitaka Matsusue
Journal: Acta Orthop Date: 2009-12 Impact factor: 3.717

Chondrocyte behavior in fibrin glue in vitro.

1. Crosslinkable hydrogels derived from cartilage, meniscus, and tendon tissue.

2. Next Generation Mesenchymal Stem Cell (MSC)-Based Cartilage Repair Using Scaffold-Free Tissue Engineered Constructs Generated with Synovial Mesenchymal Stem Cells.

Review 3. Scaffold-free, stem cell-based cartilage repair.

4. Repair of Osteochondral Defects in Rabbit Knee Using Menstrual Blood Stem Cells Encapsulated in Fibrin Glue: A Good Stem Cell Candidate for the Treatment of Osteochondral Defects.

5. Culture of chondrocytes in alginate surrounded by fibrin gel: characteristics of the cells over a period of eight weeks.

6. Autologous chondrocyte implantation in the knee using fibrin.

7. A tissue engineered osteochondral plug: an in vitro morphological evaluation.

8. Engineering of functional cartilage tissue using stem cells from synovial lining: a preliminary study.

9. Optimization of cryopreservative procedures for human articular cartilage chondrocytes.

10. Effect of dynamic compressive loading and its combination with a growth factor on the chondrocytic phenotype of 3-dimensional scaffold-embedded chondrocytes.