PURPOSE: To determine the frequency of stability in malignant microcalcifications and its relationship to specific histologic diagnoses. MATERIALS AND METHODS: During a 34-month period, microcalcifications were proved malignant in 182 patients referred for needle-guided biopsy. In 105 patients, the mammograms were compared with one or more than one previous mammogram. These patients were classified on the basis of interval change in two groups: those with stable and those with increasing or new microcalcifications. The histologic diagnoses were reviewed. RESULTS: Microcalcifications were stable for 8-63 months (mean, 25.4 months) in 26 patients (24.8%), only three (12%) of whom had invasive ductal carcinoma, which was found in 29 (37%) of the 79 patients with increasing or new microcalcifications. CONCLUSION: The odds for presence of invasive ductal carcinoma are statistically significantly lower (P < .025) among patients with stable microcalcifications than among those with increasing or new microcalcifications. Stability of indeterminate or suspicious microcalcifications is unreliable for exclusion of a diagnosis of malignancy.
PURPOSE: To determine the frequency of stability in malignant microcalcifications and its relationship to specific histologic diagnoses. MATERIALS AND METHODS: During a 34-month period, microcalcifications were proved malignant in 182 patients referred for needle-guided biopsy. In 105 patients, the mammograms were compared with one or more than one previous mammogram. These patients were classified on the basis of interval change in two groups: those with stable and those with increasing or new microcalcifications. The histologic diagnoses were reviewed. RESULTS: Microcalcifications were stable for 8-63 months (mean, 25.4 months) in 26 patients (24.8%), only three (12%) of whom had invasive ductal carcinoma, which was found in 29 (37%) of the 79 patients with increasing or new microcalcifications. CONCLUSION: The odds for presence of invasive ductal carcinoma are statistically significantly lower (P < .025) among patients with stable microcalcifications than among those with increasing or new microcalcifications. Stability of indeterminate or suspicious microcalcifications is unreliable for exclusion of a diagnosis of malignancy.
Authors: Gisela Lg Menezes; Gonneke Ao Winter-Warnars; Eva L Koekenbier; Emma J Groen; Helena M Verkooijen; Ruud M Pijnappel Journal: J Med Screen Date: 2017-07-10 Impact factor: 2.136
Authors: Monica Marro; Anna M Rodríguez-Rivero; Cuauhtémoc Araujo-Andrade; Maria Teresa Fernández-Figueras; Laia Pérez-Roca; Eva Castellà; Jordi Navinés; Antonio Mariscal; Joan Francesc Julián; Pau Turon; Pablo Loza-Alvarez Journal: Cancers (Basel) Date: 2021-05-28 Impact factor: 6.639
Authors: P Taourel; D Hoa; C Chaveron; C Balu-Maestro; D Gros; M C Baranzelli; F Ettore; M F Bretz-Grenier; P Roger Journal: Eur Radiol Date: 2008-03-20 Impact factor: 7.034