Literature DB >> 8206389

A HeLa-cell-encoded p21 is homologous to transcription elongation factor SII.

C H Yeh1, A J Shatkin.   

Abstract

A 1.2-kb cDNA clone isolated from a HeLa cell library contains an open reading frame encoding a new protein (p21) of 21 kDa that is approx. 48% similar to members of the eukaryotic transcription elongation factor SII (TFIIS) family. The deduced amino-acid sequence of p21 indicates that it is hydrophilic, basic and contains nuclear localization signals, as well as multiple consensus phosphorylation sites.

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Year:  1994        PMID： 8206389     DOI： 10.1016/0378-1119(94)90112-0

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  4 in total

1.  Down-regulation of Rous sarcoma virus long terminal repeat promoter activity by a HeLa cell basic protein.

Authors:  C H Yeh; A J Shatkin
Journal:  Proc Natl Acad Sci U S A       Date:  1994-11-08       Impact factor: 11.205

2.  In vivo CRISPR/Cas9 knockout screen: TCEAL1 silencing enhances docetaxel efficacy in prostate cancer.

Authors:  Linda K Rushworth; Victoria Harle; Peter Repiscak; William Clark; Robin Shaw; Holly Hall; Martin Bushell; Hing Y Leung; Rachana Patel
Journal:  Life Sci Alliance       Date:  2020-10-08

3.  Down-regulation of transcription elogation factor A (SII) like 4 (TCEAL4) in anaplastic thyroid cancer.

Authors:  Junko Akaishi; Masamitsu Onda; Junichi Okamoto; Shizuyo Miyamoto; Mitsuji Nagahama; Kouichi Ito; Akira Yoshida; Kazuo Shimizu
Journal:  BMC Cancer       Date:  2006-11-01       Impact factor: 4.430

4.  hsa_circ_0101119 facilitates the progression of cervical cancer via an interaction with EIF4A3 to inhibit TCEAL6 expression.

Authors:  Xuezuo Sui; Yanchun Wang; Hui Liu
Journal:  Mol Med Rep       Date:  2021-07-19       Impact factor: 2.952
  4 in total

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