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Literature DB >> 8205357

Coexistence of papillary and medullary carcinoma of the thyroid gland-mixed or collision tumour? Clinicopathological analysis of three cases.

S F Lax¹, A Beham, D Kronberger-Schönecker, W Langsteger, H Denk.

Abstract

We present three thyroid carcinomas displaying medullary and papillary components. In two cases the papillary component was characterized by typical papillae with a fibrovascular core; in one a follicular variant of papillary carcinoma was found. The papillary component was dominant in two and the medullary in one case. One tumour showed clear-cut borders between the two components, the others displayed an intermingled pattern. Both tumour components were seen in lymph node metastases with immunostaining with antibodies to calcitonin, chromogranin A, carcinoembryonic antigen, other neuroendocrine markers and thyroglobulin. At least two of our cases are true mixed carcinomas probably arising from a common stem cell.

Entities: Disease Gene

Mesh：

Year: 1994 PMID： 8205357 DOI： 10.1007/bf00190568

Source DB: PubMed Journal: Virchows Arch ISSN： 0945-6317 Impact factor: 4.064

30 in total

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Authors: J Albores-Saavedra; T Gorraez de la Mora; F de la Torre-Rendon; E Gould
Journal: Hum Pathol Date: 1990-11 Impact factor: 3.466

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Journal: Med J Aust Date: 1984-06-09 Impact factor: 7.738

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Journal: Ann Endocrinol (Paris) Date: 1978 Impact factor: 2.478

6. Solid cell nests of the thyroid. An anatomical survey and immunohistochemical study for the presence of thyroglobulin.

Authors: H R Harach
Journal: Acta Anat (Basel) Date: 1985

7. The ultimobranchial gland and congenital thyroid abnormalities in man.

Authors: E D Williams; C E Toyn; H R Harach
Journal: J Pathol Date: 1989-10 Impact factor: 7.996

8. Carcinoma of the thyroid with a mixed medullary and follicular pattern: morphologic, immunohistochemical, and clinical laboratory studies.

Authors: M Hales; W Rosenau; M D Okerlund; M Galante
Journal: Cancer Date: 1982-10-01 Impact factor: 6.860

9. Medullary carcinoma of the thyroid gland. Clinical, pathological, and immunohistochemical features with review of the literature.

Authors: M Uribe; C M Fenoglio-Preiser; M Grimes; C Feind
Journal: Am J Surg Pathol Date: 1985-08 Impact factor: 6.394

10. Mixed medullary and follicular carcinoma of the thyroid.

Authors: M Pfaltz; C E Hedinger; J P Mühlethaler
Journal: Virchows Arch A Pathol Anat Histopathol Date: 1983

19 in total

1. RET proto-oncogene mutation in a mixed medullary-follicular thyroid carcinoma.

Authors: F Orlandi; E Chiefari; P Caraci; A Mussa; I Gonzatto; P De Giuli; D Giuffrida; A Angeli; S Filetti
Journal: J Endocrinol Invest Date: 2001-01 Impact factor: 4.256

2. Mixed medullary and follicular carcinoma of the thyroid. On the search for its histogenesis.

Authors: X Matias-Guiu
Journal: Am J Pathol Date: 1999-11 Impact factor: 4.307

3. Combined "Mixed Medullary-Follicular" and "Papillary" Carcinoma of the Thyroid with Lymph Node Metastasis.

Authors: Michio Shimizu; Mitsuyoshi Hirokawa; Virginia A. LiVolsi; Yuji Mizukami; Tanekazu Harada; Tomoo Itoh; Toshiaki Manabe
Journal: Endocr Pathol Date: 2000 Impact factor: 3.943

4. Neuroendocrine differentiation in hyalinizing trabecular tumor of the thyroid.

Authors: Yasuyoshi Shikama; Tadaharu Osawa; Nobuo Yagihashi; Hidekachi Kurotaki; Soroku Yagihashi
Journal: Virchows Arch Date: 2003-12 Impact factor: 4.064

5. True mixed medullary papillary carcinoma of the thyroid: a case report with low blood calcitonin levels.

Authors: Pablo Zoroquiain; Javiera Torres; Ignacio Goñi; Lizzet Fernández; Antonieta Solar
Journal: Endocr Pathol Date: 2012-09 Impact factor: 3.943

Review 6. Synchronous occurrence of medullary and papillary carcinoma of the thyroid in a patient with cutaneous melanoma: determination of BRAFV600E in peripheral blood and tissues. Report of a case and review of the literature.

Authors: Benedetta Fibbi; Pamela Pinzani; Francesca Salvianti; Matteo Rossi; Luisa Petrone; Maria Laura De Feo; Roberto Panconesi; Vania Vezzosi; Simonetta Bianchi; Gabriele Simontacchi; Monica Mangoni; Maurizio Pertici; Gianni Forti; Cinzia Pupilli
Journal: Endocr Pathol Date: 2014-09 Impact factor: 3.943

10. Concurrent Pheochromocytoma, Paraganglioma, Papillary Thyroid Carcinoma, and Desmoid Tumor: A Case Report with Analyses at the Molecular Level.

Authors: Lucio Scopsi; Luca Cozzaglio; Paola Collini; Maria Gullo; Italia Bongarzone; Monica Giarola; Paolo Radice; Leandro Gennari
Journal: Endocr Pathol Date: 1998 Impact factor: 3.943