Literature DB >> 8203862

Development of experimental respiratory infections in neutropenic rats with either penicillin-resistant Streptococcus pneumoniae or beta-lactamase-producing Haemophilus influenzae.

G M Smith1, K H Abbott.   

Abstract

Acute respiratory infections with penicillin-resistant strains of Streptococcus pneumoniae and a beta-lactamase-producing strain of Haemophilus influenzae were established in neutropenic weanling rats. By use of nonsurgical intrabronchial instillation of the bacteria suspended in molten agar, reproducible, acute respiratory infections suitable for experimental antibiotic efficacy studies were established.

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Year:  1994        PMID： 8203862      PMCID： PMC284506          DOI： 10.1128/AAC.38.3.608

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Decreased susceptibility of penicillin-resistant pneumococci to twenty-four beta-lactam antibiotics.

Authors:  J Liñares; T Alonso; J L Pérez; J Ayats; M A Domínguez; R Pallarés; R Martín
Journal:  J Antimicrob Chemother       Date:  1992-09       Impact factor: 5.790

2.  A rat model of prolonged pulmonary infection due to nontypable Haemophilus influenzae.

Authors:  L N Slater
Journal:  Am Rev Respir Dis       Date:  1990-12

Review 3.  Antimicrobial resistance in Streptococcus pneumoniae: an overview.

Authors:  P C Appelbaum
Journal:  Clin Infect Dis       Date:  1992-07       Impact factor: 9.079

4.  A rat model of chronic respiratory infection with Pseudomonas aeruginosa.

Authors:  H A Cash; D E Woods; B McCullough; W G Johanson; J A Bass
Journal:  Am Rev Respir Dis       Date:  1979-03

5.  Experimental pneumonia due to Haemophilus influenzae: observations on pathogenesis and treatment.

Authors:  A L Esposito; J E Pennington
Journal:  J Infect Dis       Date:  1984-05       Impact factor: 5.226

6.  Intercontinental spread of a multiresistant clone of serotype 23F Streptococcus pneumoniae.

Authors:  R Muñoz; T J Coffey; M Daniels; C G Dowson; G Laible; J Casal; R Hakenbeck; M Jacobs; J M Musser; B G Spratt
Journal:  J Infect Dis       Date:  1991-08       Impact factor: 5.226

7.  Rat model of chronic lung infections caused by non-typable Haemophilus influenzae.

Authors:  I Maciver; S H Silverman; M R Brown; T O'Reilly
Journal:  J Med Microbiol       Date:  1991-09       Impact factor: 2.472

8.  Influence of clavulanic acid on the activity of amoxicillin against an experimental Streptococcus pneumoniae-Staphylococcus aureus mixed respiratory infection.

Authors:  G M Smith; R J Boon; A S Beale
Journal:  Antimicrob Agents Chemother       Date:  1990-02       Impact factor: 5.191

9.  A simple non-surgical method of intrabronchial instillation for the establishment of respiratory infections in the rat.

Authors:  G Smith
Journal:  Lab Anim       Date:  1991-01       Impact factor: 2.471

10.  Bactericidal effects of co-amoxiclav (amoxycillin clavulanic acid) against a Legionella pneumophila pneumonia in the immunocompromised weanling rat.

Authors:  G M Smith; K H Abbott; R Sutherland
Journal:  J Antimicrob Chemother       Date:  1992-10       Impact factor: 5.790
  10 in total
  9 in total

1.  Efficacy of high-dose amoxicillin-clavulanate against experimental respiratory tract infections caused by strains of Streptococcus pneumoniae.

Authors:  G Woodnutt; V Berry
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

2.  Two pharmacodynamic models for assessing the efficacy of amoxicillin-clavulanate against experimental respiratory tract infections caused by strains of Streptococcus pneumoniae.

Authors:  G Woodnutt; V Berry
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

3.  Activity of amoxicillin-clavulanate against penicillin-resistant Streptococcus pneumoniae in an experimental respiratory infection model in rats.

Authors:  G M Smith; B Slocombe; K H Abbott; L W Mizen
Journal:  Antimicrob Agents Chemother       Date:  1998-04       Impact factor: 5.191

4.  Development of a new experimental model of penicillin-resistant Streptococcus pneumoniae pneumonia and amoxicillin treatment by reproducing human pharmacokinetics.

Authors:  L Piroth; L Martin; A Coulon; C Lequeu; M Duong; M Buisson; H Portier; P Chavanet
Journal:  Antimicrob Agents Chemother       Date:  1999-10       Impact factor: 5.191

5.  Efficacy of CS-834 against experimental pneumonia caused by penicillin-susceptible and -resistant Streptococcus pneumoniae in mice.

Authors:  T Fukuoka; H Kawada; A Kitayama; T Koga; M Kubota; T Harasaki; Y Kamai; S Ohya; H Yasuda; M Iwata; S Kuwahara
Journal:  Antimicrob Agents Chemother       Date:  1998-01       Impact factor: 5.191

6.  Development of experimental pneumonia by infection with penicillin-insensitive Streptococcus pneumoniae in guinea pigs and their treatment with amoxicillin, cefotaxime, and meropenem.

Authors:  C Ponte; A Parra; E Nieto; F Soriano
Journal:  Antimicrob Agents Chemother       Date:  1996-12       Impact factor: 5.191

Review 7.  Animal models of Streptococcus pneumoniae disease.

Authors:  Damiana Chiavolini; Gianni Pozzi; Susanna Ricci
Journal:  Clin Microbiol Rev       Date:  2008-10       Impact factor: 26.132

8.  Bacteriological efficacies of three macrolides compared with those of amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae.

Authors:  V Berry; C E Thorburn; S J Knott; G Woodnutt
Journal:  Antimicrob Agents Chemother       Date:  1998-12       Impact factor: 5.191

9.  Baseline microbiota composition modulates antibiotic-mediated effects on the gut microbiota and host.

Authors:  Aonghus Lavelle; Thomas Walter Hoffmann; Hang-Phuong Pham; Philippe Langella; Eric Guédon; Harry Sokol
Journal:  Microbiome       Date:  2019-08-02       Impact factor: 14.650
  9 in total

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