Literature DB >> 8202031

LCH-I: a randomized trial of etoposide vs. vinblastine in disseminated Langerhans cell histiocytosis. The Histiocyte Society.

S Ladisch1, H Gadner, M Aricò, V Broadbent, N Grois, A Jacobson, D Komp, H S Nicholson.   

Abstract

An international randomized trial in Langerhans cell histiocytosis (LCH) has been initiated by the Histiocyte Society. This report reviews the rationale, design, and progress of LCH-I, which compares etoposide (VP-16) and vinblastine in the treatment of disseminated LCH. Data on the risk of etoposide-associated (therapy-induced) malignancy, in the setting of histiocytosis, are reviewed. The available evidence leads to the recommendation that the study of etoposide in LCH should be continued.

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Year:  1994        PMID： 8202031     DOI： 10.1002/mpo.2950230207

Source DB:  PubMed          Journal:  Med Pediatr Oncol        ISSN： 0098-1532


  12 in total

1.  Langerhans Cell Histiocytosis (LCH) in Egyptian Children: Does Reactivation Affect the Outcome?

Authors:  Mohamed Sedky Mahmoud Sedky; Hany Abdel Rahman; Emad Moussa; Hala Taha; Tarek Raafat; Omayma Hassanein
Journal:  Indian J Pediatr       Date:  2015-07-03       Impact factor: 1.967

2.  Prognostic significance of gelsolin and MMP12 in Langerhans cell histiocytosis.

Authors:  Jong-Jin Seo; Taeshik Cho; Sun-Young Kim; Ibrahim Nassour; Hee-Jin Kim; Yeon-Jung Lim; Kyung-Nam Koh; Ho-Joon Im
Journal:  Korean J Hematol       Date:  2012-12-24

3.  A multicentre retrospective survey of Langerhans' cell histiocytosis: 348 cases observed between 1983 and 1993. The French Langerhans' Cell Histiocytosis Study Group.

Authors: 
Journal:  Arch Dis Child       Date:  1996-07       Impact factor: 3.791

4.  Intralesional corticosteroid therapy for mandibular Langerhans cell histiocytosis preserving the intralesional tooth germ.

Authors:  Antonios Moralis; Martin Kunkel; Norbert Kleinsasser; Urs Müller-Richter; Torsten Eugen Reichert; Oliver Driemel
Journal:  Oral Maxillofac Surg       Date:  2008-07

5.  Long-term MR imaging course of neurodegenerative Langerhans cell histiocytosis.

Authors:  H Prosch; N Grois; M Wnorowski; M Steiner; D Prayer
Journal:  AJNR Am J Neuroradiol       Date:  2007 Jun-Jul       Impact factor: 3.825

6.  Improvement of Erdheim-Chester disease in two patients by sequential treatment with vinblastine and mycophenolate mofetil.

Authors:  Michael C Jendro; Henning Zeidler; Herbert Rosenthal; Hermann Haller; Anke Schwarz
Journal:  Clin Rheumatol       Date:  2003-11-07       Impact factor: 2.980

Review 7.  Treatment of Langerhans cell histiocytosis--evolution and current approaches.

Authors:  S Ladisch; H Gadner
Journal:  Br J Cancer Suppl       Date:  1994-09

Review 8.  Langerhans cell histiocytosis.

Authors:  Kevin Bradford Hoover; Daniel I Rosenthal; Henry Mankin
Journal:  Skeletal Radiol       Date:  2006-10-07       Impact factor: 2.128

Review 9.  Pulmonary langerhans cell histiocytosis.

Authors:  Harpreet S Suri; Eunhee S Yi; Gregorz S Nowakowski; Robert Vassallo
Journal:  Orphanet J Rare Dis       Date:  2012-03-19       Impact factor: 4.123

10.  Radiotherapy in langerhans cell histiocytosis - a rare indication in a rare disease.

Authors:  Jan Kriz; Hans Theodor Eich; Frank Bruns; Reinhard Heyd; Ulrich Schäfer; Uwe Haverkamp; Jens Büntzel; Heinrich Seegenschmiedt; Oliver Micke
Journal:  Radiat Oncol       Date:  2013-10-09       Impact factor: 3.481
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