Literature DB >> 819993

Thyrotropin releasing hormone: development of inactivation system during maturation of the rat.

J T Neary, J D Kieffer, P Federico, H Mover, F Maloof, M Soodak.   

Abstract

Whereas thyrotropin releasing hormone is rapidly and extensively degraded by plasma of adult rats, no appreciable loss of biological or immunological activity is caused by plasma from rats 4 or 16 days old. The plasma of neonatal rats does not appear to contain an inhibitor of thyrotropin releasing hormone peptidase or a peptidase with altered substrate affinity. The development of an active peptidase in rat plasma suggests a physiological role for inactivation of thyrotropin releasing hormone.

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Year:  1976        PMID： 819993     DOI： 10.1126/science.819993

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Thyrotropin-releasing hormone-like material in the rat retina: changes due to environmental lighting.

Authors:  J M Schaeffer; M J Brownstein; J Axelrod
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

2.  Ontogenetic patterns of thyrotropin-releasing hormone-like material in rat hypothalamus, pancreas, and retina: selective effect of light deprivation.

Authors:  E Martino; H Seo; A Lernmark; S Refetoff
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

Review 3.  Is all cyclo(His-Pro) derived from thyrotropin-releasing hormone?

Authors:  C Prasad; A Jayaraman; H J Robertson; J K Rao
Journal:  Neurochem Res       Date:  1987-09       Impact factor: 3.996

4.  Lower levels of thyrotropin-releasing hormone-degrading activity in human cord and in maternal sera than in the serum of euthyroid, nonpregnant adults.

Authors:  J T Neary; C Nakamura; I J Davies; M Soodak; F Maloof
Journal:  J Clin Invest       Date:  1978-07       Impact factor: 14.808

5.  Thyrotropin-releasing hormone is not required for thyrotropin secretion in the perinatal rat.

Authors:  T Theodoropoulos; L E Braverman; A G Vagenakis
Journal:  J Clin Invest       Date:  1979-04       Impact factor: 14.808

6.  Thyrotropin-releasing hormone in the systemic circulation of the neonatal rat is derived from the pancreas and other extraneural tissues.

Authors:  D Engler; M F Scanlon; I M Jackson
Journal:  J Clin Invest       Date:  1981-03       Impact factor: 14.808

7.  Maturational patterns of iodothyronine phenolic and tyrosyl ring deiodinase activities in rat cerebrum, cerebellum, and hypothalamus.

Authors:  M M Kaplan; K A Yaskoski
Journal:  J Clin Invest       Date:  1981-04       Impact factor: 14.808
  7 in total

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