Literature DB >> 8197047

Complete heart block and torsade de pointes associated with thioridazine poisoning.

D T Hulisz1, S L Dasa, L D Black, D E Heiselman.   

Abstract

A 72-year-old woman attempted suicide with thioridazine 3000 mg and 60 tablets of acetaminophen 325 mg plus codeine 30 mg. She was semicomatose and had persistent third-degree atrioventricular block, progressive hypotension, and an episode of torsade de pointes. Heart block, arrhythmias, and hypotension resolved within 48 hours, and the patient recovered without adverse sequelae.

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Year:  1994        PMID: 8197047

Source DB:  PubMed          Journal:  Pharmacotherapy        ISSN: 0277-0008            Impact factor:   4.705


  5 in total

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Review 2.  Antipsychotic-related QTc prolongation, torsade de pointes and sudden death.

Authors:  Peter M Haddad; Ian M Anderson
Journal:  Drugs       Date:  2002       Impact factor: 9.546

3.  Electrocardiogram and cardiovascular changes in thioridazine and chlorpromazine poisoning.

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4.  In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile.

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Journal:  Oncotarget       Date:  2019-05-28

5.  Fluphenazine decanoate-induced bradycardia: A case report.

Authors:  Mahsa Kamali; Mehran Zarghami; Marzieh Azizi; Forouzan Elyasi
Journal:  Neuropsychopharmacol Rep       Date:  2022-04-03
  5 in total

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