Literature DB >> 8188199

Savings in hospital bed-days related to treatment with clozapine.

W H Reid1, M Mason, M Toprac.   

Abstract

OBJECTIVE: The authors' aim was to determine whether clozapine was associated with a decrease in state hospital bed-days for patients with chronic schizophrenia.
METHODS: Patients were started on clozapine in a state facility and were followed while taking the medication for 1.5 years (N = 172), two years (N = 86), and 2.5 years (N = 53). Patients' number of bed-days before starting clozapine was compared with those during the follow-up period.
RESULTS: Bed-days were reduced by an average of 132 days per year after 1.5 years, 166 days per year after two years, and 201 days per year after 2.5 years (p < .001). During the final 180 days of each follow-up period, only 23 to 30 percent of patients were continuously hospitalized, compared with 56 to 64 percent before clozapine. Forty to 57 percent of patients had no hospital days at all during the last 180 days of follow-up.
CONCLUSIONS: Based on hospital costs of $250 per patient per day, this reduction in bed-days could result in gross savings of about $33,000 per patient per year at 1.5 years, $41,500 per patient per year at two years, and $50,250 per patient per year at 2.5 years. Hospital patients are conspicuous targets for clozapine funding, since bed-days represent an easily measured expense. Nevertheless, community treatment should be an even higher priority, since most chronic mentally ill persons are outpatients.

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Year:  1994        PMID: 8188199     DOI: 10.1176/ps.45.3.261

Source DB:  PubMed          Journal:  Hosp Community Psychiatry        ISSN: 0022-1597


  11 in total

1.  The cost-effectiveness of clozapine: a survey of the literature.

Authors:  S Morris; T Hogan; A McGuire
Journal:  Clin Drug Investig       Date:  1998       Impact factor: 2.859

2.  Multiple outcome assessment in a study of the cost-effectiveness of clozapine in the treatment of refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia.

Authors:  R Rosenheck; J Cramer; W Xu; J Grabowski; R Douyon; J Thomas; W Henderson; D Charney
Journal:  Health Serv Res       Date:  1998-12       Impact factor: 3.402

3.  Clozapine for Treatment-Resistant Schizophrenia: Still the Gold Standard?

Authors:  David M Taylor
Journal:  CNS Drugs       Date:  2017-03       Impact factor: 5.749

4.  Clinical and economic outcomes of olanzapine compared with haloperidol for schizophrenia. Results from a randomised clinical trial.

Authors:  S H Hamilton; D A Revicki; E T Edgell; L A Genduso; G Tollefson
Journal:  Pharmacoeconomics       Date:  1999-05       Impact factor: 4.981

5.  Olanzapine versus risperidone. A prospective comparison of clinical and economic outcomes in schizophrenia.

Authors:  E T Edgell; S W Andersen; B M Johnstone; B Dulisse; D Revicki; A Breier
Journal:  Pharmacoeconomics       Date:  2000-12       Impact factor: 4.981

6.  Cost-benefit analysis of risperidone and clozapine in the treatment of schizophrenia in Israel.

Authors:  G Ginsberg; S Shani; B Lev
Journal:  Pharmacoeconomics       Date:  1998-02       Impact factor: 4.981

Review 7.  Measuring quality of life in patients with schizophrenia.

Authors:  A G Awad; L N Voruganti; R J Heslegrave
Journal:  Pharmacoeconomics       Date:  1997-01       Impact factor: 4.981

Review 8.  Patient compliance with drug therapy in schizophrenia. Economic and clinical issues.

Authors:  E Lindström; K Bingefors
Journal:  Pharmacoeconomics       Date:  2000-08       Impact factor: 4.981

Review 9.  Impact of atypical antipsychotics on quality of life in patients with schizophrenia.

Authors:  A George Awad; Lakshmi N P Voruganti
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

10.  Pharmacoeconomic assessment of olanzapine in the treatment of refractory schizophrenia based on a pilot clinical study.

Authors:  J A Sacristán; J C Gómez; J Martín; E García-Bernardo; V Peralta; E Alvarez; M Gurpegui
Journal:  Clin Drug Investig       Date:  1998       Impact factor: 2.859

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