Literature DB >> 8185398

Surgical management of esophageal cancer. A decade of change.

J S Bolton1, J L Ochsner, A A Abdoh.   

Abstract

OBJECTIVE: To examine trends for use of transhiatal esophagectomy (THE) and to relate outcome variables to changes in use, controlling for preoperative risk.
BACKGROUND: High operative morbidity and mortality rates are reported with conventional transthoracic esophagectomy (TTE). Transhiatal esophagectomy has been proposed as an alternative but is controversial.
METHODS: In this retrospective study divided into early and late time periods, outcome variables were subjected to univariate and multivariate analyses.
RESULTS: Use of THE increased significantly in the late period (p < 0.0001). Patients who had THE had significantly higher American Society of Anesthesiologists (ASA) risk scores (p < 0.001). By the late period, 92% of patients with ASA III/IV scores were resected by THE. Postoperative morbidity decreased significantly and operative mortality decreased from 15% to 0% (p < 0.01) between the early and late time periods. By multivariate analysis, ASA > or = III and TTE were associated with adverse surgical outcome. Pathologic stage determined disease-free survival, which was 37% at 3 years for all survivors.
CONCLUSIONS: Increased use of THE results in better operative outcome and does not adversely affect disease-free survival.

Entities:  

Mesh:

Year:  1994        PMID: 8185398      PMCID: PMC1243172          DOI: 10.1097/00000658-199405000-00005

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  10 in total

1.  Immunisation against experimental staphylococcal infection with coagulase-rich preparations.

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Journal:  Am J Surg       Date:  1989-11       Impact factor: 2.565

5.  Esophagectomy without thoracotomy.

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Journal:  Ann Thorac Surg       Date:  1989-05       Impact factor: 4.330

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Authors:  V Velanovich
Journal:  Surgery       Date:  1991-03       Impact factor: 3.982

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Authors:  R Earlam; J R Cunha-Melo
Journal:  Br J Surg       Date:  1980-06       Impact factor: 6.939

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Authors:  R Giuli; H Sancho-Garnier
Journal:  Surgery       Date:  1986-05       Impact factor: 3.982

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Journal:  Ann Thorac Surg       Date:  1986-03       Impact factor: 4.330

  10 in total
  4 in total

1.  Transhiatal esophagectomy: clinical experience and refinements.

Authors:  M B Orringer; B Marshall; M D Iannettoni
Journal:  Ann Surg       Date:  1999-09       Impact factor: 12.969

Review 2.  Transhiatal esophagectomy for treatment of benign and malignant esophageal disease.

Authors:  M B Orringer; B Marshall; M D Iannettoni
Journal:  World J Surg       Date:  2001-02       Impact factor: 3.352

3.  A hospital's annual rate of esophagectomy influences the operative mortality rate.

Authors:  M G Patti; C U Corvera; R E Glasgow; L W Way
Journal:  J Gastrointest Surg       Date:  1998 Mar-Apr       Impact factor: 3.267

4.  Epithelial cells in bone marrow of oesophageal cancer patients: a significant prognostic factor in multivariate analysis.

Authors:  S Thorban; R Rosenberg; R Busch; R J Roder
Journal:  Br J Cancer       Date:  2000-07       Impact factor: 7.640

  4 in total

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