Literature DB >> 818016

Adjuvant effect of cord factor, a mycobacterial lipid.

R Saito, A Tanaka, K Sugiyama, I Azuma, Y Yamamura.   

Abstract

Cord factor was a good adjuvant in mice and rats but exerted little if any adjuvant effect in guinea pigs. In rats, cord factor not only enhanced antibody production but also induced delayed hypersensitivity. Wax D was a weak adjuvant in mice. Cord factor caused a marked inflammatory swelling at the sites of injection in mice, but it caused no such swelling in rats and guinea pigs.

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Year:  1976        PMID: 818016      PMCID: PMC420677          DOI: 10.1128/iai.13.3.776-781.1976

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  14 in total

1.  FRACTIONATION AND CHARACTERIZATION OF WAX D, A MACROMOLECULAR PEPTIDOGLYCOLIPID OF MYCOBACTERIUM TUBERCULOSIS. I. BIOCHEMICAL INVESTIGATIONS OF WAX D OF HUMAN STRAIN H37RA.

Authors:  A TANAKA; M KITAGAWA
Journal:  Biochim Biophys Acta       Date:  1965-02-01

2.  Studies on the chemistry of the cord factor of Mycobacterium tuberculosis.

Authors:  H NOLL; H BLOCH
Journal:  J Biol Chem       Date:  1955-05       Impact factor: 5.157

3.  The influence of components of M. tuberculosis and other Mycobacteria upon antibody production to ovalbumin.

Authors:  R G WHITE; L BERNSTOCK; R G JOHNS; E LEDERER
Journal:  Immunology       Date:  1958-01       Impact factor: 7.397

4.  Biologically active components from mycobacterial cell walls. I. Isolation and composition of cell wall skeleton and component P3.

Authors:  I Azuma; E E Ribi; T J Meyer; B Zbar
Journal:  J Natl Cancer Inst       Date:  1974-01       Impact factor: 13.506

5.  Biologically active components from mycobacterial cell walls. II. Suppression and regression of strain-2 guinea pig hepatoma.

Authors:  T J Meyer; E E Ribi; I Azuma; B Zbar
Journal:  J Natl Cancer Inst       Date:  1974-01       Impact factor: 13.506

6.  A simple method of preparing protein-erythrocyte conjugates for hemagglutination tests.

Authors:  A W Frisch; R H Persellin
Journal:  Proc Soc Exp Biol Med       Date:  1967-02

7.  The use of a wate-soluble carbodiimide as a coupling reagent in the passive hemagglutination test.

Authors:  H M Johnson; K Brenner; H E Hall
Journal:  J Immunol       Date:  1966-12       Impact factor: 5.422

8.  Immunological adjuvants. VI. An acetylated mycobacterial adjuvant lacking competing antigenicity.

Authors:  A Tanaka; T Ishibashi; K Sugiyama; M Takamoto
Journal:  Z Immunitatsforsch Exp Klin Immunol       Date:  1971-11

9.  Biologically active components from mycobacterial cell walls. IV. Protection of mice against aerosol infection with virulent mycobacterium tuberculosis.

Authors:  E Ribi; T J Meyer; I Azuma; R Parker; W Brehmer
Journal:  Cell Immunol       Date:  1975-03       Impact factor: 4.868

10.  Synergistic action of cord factor and mycobacterial sulfatides on mitochondria.

Authors:  M Kato; M B Goren
Journal:  Infect Immun       Date:  1974-10       Impact factor: 3.441

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  17 in total

1.  Granuloma formation in lungs of mice after intravenous administration of emulsified trehalose-6,6'-dimycolate (cord factor): reaction intensity depends on size distribution of the oil droplets.

Authors:  E Yarkoni; H J Rapp
Journal:  Infect Immun       Date:  1977-11       Impact factor: 3.441

2.  Adjuvant effects of trehalose dimycolate on the antibody response to type III pneumococcal polysaccharide.

Authors:  P J Baker; M B Fauntleroy; P W Stashak; J R Hiernaux; J L Cantrell; J A Rudbach
Journal:  Infect Immun       Date:  1989-03       Impact factor: 3.441

3.  Nonspecific immunostimulant activities of synthetic trehalose-6,6'-diesters (lower homologs of cord factor).

Authors:  M Parant; F Audibert; F Parant; L Chedid; E Soler; J Polonsky; E Lederer
Journal:  Infect Immun       Date:  1978-04       Impact factor: 3.441

4.  Failure of trehalose-6,6'-dimycolate (P3 or cord factor) to enhance endotoxin lethality in mice.

Authors:  E Yarkoni; M S Meltzer; H J Rapp
Journal:  Infect Immun       Date:  1976-12       Impact factor: 3.441

Review 5.  Mycobacterium.

Authors:  L Barksdale; K S Kim
Journal:  Bacteriol Rev       Date:  1977-03

6.  Elevated adjuvanticity of non-acid-fast mycobacteria.

Authors:  Y Kondo; T Toida
Journal:  Infect Immun       Date:  1979-10       Impact factor: 3.441

7.  Granulomagenic activity of serologically active glycolipids from Mycobacterium bovis BCG.

Authors:  Z Reggiardo; A K Shamsuddin
Journal:  Infect Immun       Date:  1976-12       Impact factor: 3.441

8.  Regression of a transplanted guinea pig hepatoma after intralesional injection of an emulsified mixture of endotoxin and mycobacterial sulfolipid.

Authors:  E Yarkoni; M B Goren; H J Rapp
Journal:  Infect Immun       Date:  1979-05       Impact factor: 3.441

9.  Adjuvant activity of synthetic N-acetylmuramyl peptides in rats.

Authors:  A Tanaka; R Saito; K Sugiyama; I Morisaki; S Kotani
Journal:  Infect Immun       Date:  1977-01       Impact factor: 3.441

10.  Nonspecific resistance against infection with Salmonella typhi and Salmonella typhimurium induced in mice by cord factor (trehalose-6,6'-dimycolate) and its analogues.

Authors:  E Yarkoni; A Bekierkunst
Journal:  Infect Immun       Date:  1976-11       Impact factor: 3.441

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