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Literature DB >> 818006

C1 and human platelets. II. Detection by immunological methods and role.

J L Wautier, G M Tobelem, A P Peltier, J P Caen.

Abstract

A C1 haemolytic activity was previously shown to be associated with platelets. The presence of C1 on human gel filtered platelets is confirmed by Ouchterlony analysis, and platelet aggregation induced by anti-c1 q antisera. After cleavage of C1 by EDTA, platelet aggregation induced by aggregated was decreased and was restored by the addition of C1. The possible role of C1 in human platelet aggregation induced by aggregated immunoglobulins or immune complexes is discussed.

Entities: Chemical Disease Species

Mesh：

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Year: 1976 PMID： 818006 PMCID： PMC1445024

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

18 in total

Review 1. Immunologic mechanisms of platelet damage.

Authors: A G Osler; R P Siraganian
Journal: Prog Allergy Date: 1972

2. Aggregation of human gel-filtered platelets. Requirement of apyrase and proteins.

Authors: S Levy-Toledano; F Rendu; P Besson; J Caen
Journal: Rev Eur Etud Clin Biol Date: 1972-05

Review 3. The effects of immune complexes on blood platelets and their relationship to complement activation.

Authors: S L Pfueller; E F Lüscher
Journal: Immunochemistry Date: 1972-11

4. Qualitative description of factors involved in the retraction and lysis of dilute whole blood clots and in the aggregation and retraction of platelets.

Authors: F B Taylor; H J Müller-Eberhard
Journal: J Clin Invest Date: 1970-11 Impact factor: 14.808

5. Studies of the mechanisms of the human platelet release reaction induced by immunologic stimuli. I. Complement-dependent and complement-independent reactions.

Authors: S L Pfueller; E F Lüscher
Journal: J Immunol Date: 1974-03 Impact factor: 5.422

6. The effects of aggregated immunoglobulins on human blood platelets in relation to their complement-fixing abilities. I. Studies of immunoglobulins of different types.

Authors: S L Pfueller; E F Lüscher
Journal: J Immunol Date: 1972-09 Impact factor: 5.422

Review 7. Platelet aggregation by large molecules.

Authors: E F Lüscher; S L Pfueller; P Massini
Journal: Ser Haematol Date: 1973

8. Release of serotonin from human platelets induced by aggregated immunoglobulins of different classes and subclasses.

Authors: P M Henson; H L Spiegelberg
Journal: J Clin Invest Date: 1973-05 Impact factor: 14.808

9. Chromatographic resolution of the first component of human complement into three activities.

Authors: I H LEPOW; G B NAFF; E W TODD; J PENSKY; C F HINZ
Journal: J Exp Med Date: 1963-06-01 Impact factor: 14.307

7 in total

1. C1 and human platelets. III. Role of C1 subcomponents in platelet aggregation induced by aggregated IgG.

Authors: J L Wautier; H Souchon; L C Solal; A P Peltier; J P Caen
Journal: Immunology Date: 1976-10 Impact factor: 7.397

2. Inhibition of the reconstitution of the haemolytic activity of the first component of human complement by a pepsin-derived fragment of subcomponent C1q.

Authors: K B Reid; R B Sim; A P Faiers
Journal: Biochem J Date: 1977-02-01 Impact factor: 3.857

7. Enhancement of platelet response to immune complexes and IgG aggregates by lipid A-rich bacterial lipopolysaccharides.

Authors: M H Ginsberg; P M Henson
Journal: J Exp Med Date: 1978-01-01 Impact factor: 14.307