Literature DB >> 817923

5-thio-D-glucose: o-diphenoloxidase inhibition as its mechanism of action.

K Prabhakaran.   

Abstract

5-Thio-D-glucose completely inhibited o-diphenoloxidase from animal as well as plant sources. It has been reported that thioglucose suppresses spermatogenesis in mice and also insect metamorphosis, probably through inhibition of glucose transport. Inhibition of o-diphenoloxidase (which is active in spermatozoa and insect larvae) is suggested as an alternative mechanism of action of thioglucose.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 817923     DOI： 10.1007/BF01937736

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Comparative biochemistry of the phenolase complex.

Authors:  H S MASON
Journal:  Adv Enzymol Relat Subj Biochem       Date:  1955

2.  Temporary sterility produced in male mice by 5-thio-D-glucose.

Authors:  J R Zysk; A A Bushway; R L Whistler; W W Carlton
Journal:  J Reprod Fertil       Date:  1975-10

3.  Side effects of 5-thio-d-glucose.

Authors:  J W Kalat
Journal:  Science       Date:  1974-12-20       Impact factor: 47.728

4.  Biochemistry of melanin formation.

Authors:  A B LERNER; T B FITZPATRICK
Journal:  Physiol Rev       Date:  1950-01       Impact factor: 37.312

5.  Diabetogenic action of 5-thio-D-glucopyranose in rats.

Authors:  D J Hoffman; R L Whistler
Journal:  Biochemistry       Date:  1968-12       Impact factor: 3.162

6.  The melanizing activity of the semen of buffalo bulls and its relation to the proportion of liver spermatozoa.

Authors:  K P Pant; D P Mukherjee
Journal:  J Reprod Fertil       Date:  1971-04

7.  Particulate nature of o-diphenoloxidase in Mycobacterium leprae and assay of the enzyme by the radioisotope technique.

Authors:  K Prabhakaran; E B Harris; W F Kirchheimer
Journal:  Microbios       Date:  1973 Sep-Oct

8.  Determination of in vivo alterations in a phenotype of human spermatozoa.

Authors:  D R Ackerman
Journal:  Nature       Date:  1970-09-12       Impact factor: 49.962

9.  Production of reversible infertility in rats by feeding mimosine.

Authors:  J W Hylin; I J Lichton
Journal:  Biochem Pharmacol       Date:  1965-07       Impact factor: 5.858

10.  Effect of inhibitors on phenoloxidase of Mycobacterium leprae.

Authors:  K Prabhakaran; E B Harris; W F Kirchheimer
Journal:  J Bacteriol       Date:  1969-11       Impact factor: 3.490
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.