Literature DB >> 1195257

Temporary sterility produced in male mice by 5-thio-D-glucose.

J R Zysk, A A Bushway, R L Whistler, W W Carlton.   

Abstract

When 5-thio-D-glucose was fed to male mice at daily dose levels greater than 30 mg/kg sperm development was completely inhibited within 3 weeks and remained so without impairment of libido for the experimental period of 7 weeks. Removal of this substance from the diet resulted in a resumption of sperm development and fertility within 5 to 8 weeks. Normal litters were sired by males which had recovered after this treatment.

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Year:  1975        PMID： 1195257     DOI： 10.1530/jrf.0.0450069

Source DB:  PubMed          Journal:  J Reprod Fertil        ISSN： 0022-4251


  8 in total

Review 1.  Hormonal control of Sertoli cell metabolism regulates spermatogenesis.

Authors:  Marco G Alves; Luís Rato; Rui A Carvalho; Paula I Moreira; Sílvia Socorro; Pedro F Oliveira
Journal:  Cell Mol Life Sci       Date:  2012-07-20       Impact factor: 9.261

2.  Cytotoxic effect of 5-thio-D-glucose on chronically hypoxic cells in multicell spheroids.

Authors:  C W Song; J H Sung; J J Clement; S H Levitt
Journal:  Br J Cancer Suppl       Date:  1978-06

3.  Synthesis, characterization and reactivity of carbohydrate platinum(IV) complexes with thioglycoside ligands.

Authors:  Cornelia Vetter; Papapida Pornsuriyasak; Jürgen Schmidt; Nigam P Rath; Tobias Rüffer; Alexei V Demchenko; Dirk Steinborn
Journal:  Dalton Trans       Date:  2010-06-01       Impact factor: 4.390

4.  5-thio-D-glucose: o-diphenoloxidase inhibition as its mechanism of action.

Authors:  K Prabhakaran
Journal:  Experientia       Date:  1976-02-15

5.  Effect of 5-thio-D-glucose on testicular lipids of mice.

Authors:  K Veeraragavan; S Ramakrishnan
Journal:  Experientia       Date:  1982-12-15

6.  Immunohistochemical localization of glucose transporter 1 and 3 in the scrotal and abdominal testes of a dog.

Authors:  Kyu Ri Hahn; Hyo Young Jung; Dae Young Yoo; Jong Whi Kim; Yang Hee Kim; Young Kwang Jo; Geon A Kim; Jin Young Chung; Jung Hoon Choi; In Koo Hwang; Goo Jang; Yeo Sung Yoon
Journal:  Lab Anim Res       Date:  2017-06-30

7.  Stereoselective synthesis of (+)-5-thiosucrose and (+)-5-thioisosucrose.

Authors:  Atsushi Ueda; Jinhong Pi; Yui Makura; Masakazu Tanaka; Jun'ichi Uenishi
Journal:  RSC Adv       Date:  2020-03-06       Impact factor: 4.036

Review 8.  Diabetes, insulin-mediated glucose metabolism and Sertoli/blood-testis barrier function.

Authors:  Marco G Alves; Ana D Martins; José E Cavaco; Sílvia Socorro; Pedro F Oliveira
Journal:  Tissue Barriers       Date:  2013-04-01
  8 in total

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