Literature DB >> 8177022

Delta 22-beta-muricholic acid in monoassociated rats and conventional rats.

T Kayahara1, T Tamura, Y Amuro, K Higashino, H Igimi, K Uchida.   

Abstract

Bile acids were analyzed in the bile, small and large intestines, and feces of germ-free rats after a single inoculation with one of six intestinal bacteria that had been originally isolated from human feces. Bacteroides vulgatus and Bifidobacterium longum preferentially deconjugated tauro-beta-muricholic acid and taurocholic acid, respectively. Clostridium ramosum, Peptostreptococcus productus and Lactobacillus gasseri deconjugated both bile acids, but Escherichia coli did not deconjugate either one. Rats inoculated with bacteria that deconjugated tauro-beta-muricholic acid produced delta 22-beta-muricholic acid in the feces. In contrast, delta 22-cholic acid could not be detected in rats inoculated with bacteria that deconjugated taurocholic acid.

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Year:  1994        PMID： 8177022     DOI： 10.1007/bf02536334

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  20 in total

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Journal:  J Clin Invest       Date:  1977-09       Impact factor: 14.808

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Journal:  Steroids       Date:  1973-10       Impact factor: 2.668

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Journal:  J Lipid Res       Date:  1979-03       Impact factor: 5.922

5.  Deconjugation of bile acids by human intestinal bacteria implanted in germ-free rats.

Authors:  T Chikai; H Nakao; K Uchida
Journal:  Lipids       Date:  1987-09       Impact factor: 1.880

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Journal:  Appl Environ Microbiol       Date:  1979-06       Impact factor: 4.792

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Journal:  J Lipid Res       Date:  1984-03       Impact factor: 5.922

8.  Studies on steroids. CCXXVII. Separation and determination of bile acid 7- and 12-sulphates in urine by high-performance liquid chromatography with fluorescence labelling.

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Journal:  J Chromatogr       Date:  1987-03-20

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Journal:  J Steroid Biochem       Date:  1985-04       Impact factor: 4.292

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Authors:  Y Benno; N Shiragami; K Uchida; T Yoshida; T Mitsuoka
Journal:  Antimicrob Agents Chemother       Date:  1986-01       Impact factor: 5.191
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  7 in total

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Journal:  Appl Environ Microbiol       Date:  1999-07       Impact factor: 4.792

2.  Effects of beta-lactam antibiotics on intestinal microflora and bile acid metabolism in rats.

Authors:  S Hashimoto; H Igimi; K Uchida; T Satoh; Y Benno; N Takeuchi
Journal:  Lipids       Date:  1996-06       Impact factor: 1.880

3.  Bile acid metabolism in analbuminemic rats.

Authors:  A Kambe; K Uchida; H Takase; Y Nomura; Y Adachi
Journal:  Lipids       Date:  1998-01       Impact factor: 1.880

4.  Transformation of bile acids and sterols by clostridia (fusiform bacteria) in Wistar rats.

Authors:  K Uchida; T Satoh; S Narushima; K Itoh; H Takase; K Kuruma; H Nakao; N Yamaga; K Yamada
Journal:  Lipids       Date:  1999-03       Impact factor: 1.880

5.  Chemical Synthesis of the Epimeric (23R)- and (23S)-Fluoro Derivatives of Bile Acids via Horner-Wadsworth-Emmons Reaction.

Authors:  Kaoru Omura; Yuuki Adachi; Yuuki Kobayashi; Shoutaro Sekiguchi; Biao Zhou; Takashi Iida
Journal:  Lipids       Date:  2015-07-21       Impact factor: 1.880

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Authors:  K Uchida; H Takase; Y Nomura; T Satoh; H Igimi; N Takeuchi
Journal:  Lipids       Date:  1997-04       Impact factor: 1.880

7.  Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA.

Authors:  Michael DiMarzio; Brigida Rusconi; Neela H Yennawar; Mark Eppinger; Andrew D Patterson; Edward G Dudley
Journal:  PLoS One       Date:  2017-09-14       Impact factor: 3.240
  7 in total

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