Literature DB >> 816349

Chemical selection of mutants that affect ADH activity in Drosophila. III. Effects of ethanol.

C Vigue, W Sofer.   

Abstract

A chemical selection scheme is presented for the isolation of rare Adh-positive Drosophila. It makes use of the fact that flies lacking detectable ADH activity die as adults or larvae on relatively low concentrations of ethanol in the medium. We have demonstrated that this procedure is a practical one by crossing two Adh-negative alleles, screening 1.5 x 10(6) embryos, and isolating 14 Adh-positive survivors.

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Year:  1976        PMID： 816349     DOI： 10.1007/BF00484879

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  9 in total

1.  Chemical selection of mutants that affect alcohol dehydrogenase in Drosophila. II. Use of 1-pentyne-3-ol.

Authors:  J O'Donnell; L Gerace; F Leister; W Sofer
Journal:  Genetics       Date:  1975-01       Impact factor: 4.562

Review 2.  Mutation in eukaryotes.

Authors:  C Auerbach; B J Kilbey
Journal:  Annu Rev Genet       Date:  1971       Impact factor: 16.830

Review 3.  Mechanisms of suppression.

Authors:  P E Hartman; J R Roth
Journal:  Adv Genet       Date:  1973       Impact factor: 1.944

4.  Age-dependent changes in alcohol dehydrogenase in drosophila.

Authors:  G R Dunn; T G Wilson; K B Jacobson
Journal:  J Exp Zool       Date:  1969-06

5.  Drosophila alcohol dehydrogenase. Purification and partial characterization.

Authors:  W Sofer; H Ursprung
Journal:  J Biol Chem       Date:  1968-06-10       Impact factor: 5.157

6.  Alterations of genetics material for analysis of alcohol dehydrogenase isozymes of Drosophila melanogaster.

Authors:  E H Grell; K B Jacobson; J B Murphy
Journal:  Ann N Y Acad Sci       Date:  1968-06-14       Impact factor: 5.691

7.  Adh-n5: a temperature-sensitive mutant at the Adh locus in Drosophila.

Authors:  C Vigue; W Sofer
Journal:  Biochem Genet       Date:  1974-05       Impact factor: 1.890

8.  Studies on gene conversion and its relationship to linked exchange in Drosophila melanogaster.

Authors:  A Chovnick; G H Ballantyne; D G Holm
Journal:  Genetics       Date:  1971-10       Impact factor: 4.562

9.  Chemical selection of alcohol dehydrogenase negative mutants in drosophila.

Authors:  W H Sofer; M A Hatkoff
Journal:  Genetics       Date:  1972-11       Impact factor: 4.562
  9 in total
  17 in total

1.  The partial characterization of alcohol dehydrogenase null alleles from natural populations of Drosophila melanogaster.

Authors:  A L Freeth; J B Gibson; H G de Couet
Journal:  Biochem Genet       Date:  1986-12       Impact factor: 1.890

2.  A simple method for the isolation of allelic series using male-linked translocations.

Authors:  A S Robinson; M E Riva
Journal:  Theor Appl Genet       Date:  1984-02       Impact factor: 5.699

3.  Conversion and reciprocal exchange between tandem repeats in Drosophila melanogaster.

Authors:  R Hipeau-Jacquotte; D L Brutlag; F Brégégère
Journal:  Mol Gen Genet       Date:  1989-12

4.  Genetic and biochemical properties of revertants at the rudimentary locus in Drosophila melanogaster.

Authors:  S I Tsubota; J W Fristrom
Journal:  Mol Gen Genet       Date:  1981

5.  Drosophila alcohol dehydrogenase activity in vitro and in vivo: effects of acetone feeding.

Authors:  I Papel; M Henderson; J Van Herrewege; J David; W Sofer
Journal:  Biochem Genet       Date:  1979-06       Impact factor: 1.890

6.  Biological role of alcohol dehydrogenase in the tolerance of Drosophila melanogaster to aliphatic alochols: utilization of an ADH-null mutant.

Authors:  J R David; C Bocquet; M F Arens; P Fouillet
Journal:  Biochem Genet       Date:  1976-12       Impact factor: 1.890

7.  In vitro suppression of a nonsense mutant of Drosophila melanogaster.

Authors:  E Kubli; T Schmidt; P F Martin; W Sofer
Journal:  Nucleic Acids Res       Date:  1982-11-25       Impact factor: 16.971

8.  Drosophila nonsense suppressors: functional analysis in Saccharomyces cerevisiae, Drosophila tissue culture cells and Drosophila melanogaster.

Authors:  D Garza; M M Medhora; D L Hartl
Journal:  Genetics       Date:  1990-11       Impact factor: 4.562

9.  Genetic regulation of liver alcohol dehydrogenase in Peromyscus.

Authors:  K G Burnett; M R Felder
Journal:  Biochem Genet       Date:  1978-06       Impact factor: 1.890

10.  Selection at the alcohol dehydrogenase locus of Drosophila melanogaster: effects of ethanol and temperature.

Authors:  C L Vigue; P A Weisgram; E Rosenthal
Journal:  Biochem Genet       Date:  1982-08       Impact factor: 1.890
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