Literature DB >> 8162324

Alphoid DNA diversity of a so-called monocentric Robertsonian fusion.

S Luke1, G Aggarwal, D G Stetka, R S Verma.   

Abstract

The centromeric heterochromatin of a Robertsonian translocation with t(13q14q), thought to be monocentric by conventional staining methods, was found to be dicentric using molecular techniques. The breakpoints were confined within the alphoid DNA subfamilies and fusion resulted in a compound centromere. The fragile nature of alphoid DNA sequences during Robertsonian translocation has opened new avenues in understanding other chromosomal aberrations involving centric fusion.

Mesh：

Substances：

Year:  1994        PMID： 8162324     DOI： 10.1007/bf01539457

Source DB:  PubMed          Journal:  Chromosome Res        ISSN： 0967-3849            Impact factor:   5.239


  10 in total

1.  Molecular cytogenetic evidence to characterize breakpoint regions in Robertsonian translocations.

Authors:  S W Cheung; L Sun; T Featherstone
Journal:  Cytogenet Cell Genet       Date:  1990

Review 2.  Centromeres of mammalian chromosomes.

Authors:  H F Willard
Journal:  Trends Genet       Date:  1990-12       Impact factor: 11.639

3.  Origin of human chromosome 2.

Authors:  S Luke; R S Verma
Journal:  Nat Genet       Date:  1992-09       Impact factor: 38.330

4.  Nucleolus organizer regions in translocations involving acrocentric chromosomes.

Authors:  M Mikkelsen; A Basli; H Poulsen
Journal:  Cytogenet Cell Genet       Date:  1980

5.  Molecular topography of the secondary constriction region (qh) of human chromosome 9 with an unusual euchromatic band.

Authors:  R S Verma; S Luke; J P Brennan; T Mathews; R A Conte; M J Macera
Journal:  Am J Hum Genet       Date:  1993-05       Impact factor: 11.025

6.  A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities.

Authors:  J L Hamerton; N Canning; M Ray; S Smith
Journal:  Clin Genet       Date:  1975-10       Impact factor: 4.438

7.  Human beta satellite DNA: genomic organization and sequence definition of a class of highly repetitive tandem DNA.

Authors:  J S Waye; H F Willard
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

8.  Mutation rates of structural chromosome rearrangements in man.

Authors:  P A Jacobs
Journal:  Am J Hum Genet       Date:  1981-01       Impact factor: 11.025

9.  Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

Authors:  D Pinkel; T Straume; J W Gray
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

10.  Molecular characterization of the secondary constriction region (qh) of human chromosome 9 with pericentric inversion.

Authors:  S Luke; R S Verma; R A Conte; T Mathews
Journal:  J Cell Sci       Date:  1992-12       Impact factor: 5.285
  10 in total
  2 in total

1.  Breakpoints in alpha, beta, and satellite III DNA sequences of chromosome 9 result in a variety of pericentric inversions.

Authors:  K H Ramesh; R S Verma
Journal:  J Med Genet       Date:  1996-05       Impact factor: 6.318

2.  High frequency of mutagen-induced chromatid exchanges at interstitial telomere-like DNA sequence blocks of Chinese hamster cells.

Authors:  J L Fernández; J Gosálvez; V Goyanes
Journal:  Chromosome Res       Date:  1995-08       Impact factor: 5.239
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.