Tight versus loose scleral flap closure in trabeculectomy surgery.

Thirty-two consecutive trabeculectomy patients were randomized to receive a tight scleral flap closure (15 eyes) with postoperative laser suture lysis, or a loose scleral flap closure (18 eyes) to determine differences in the surgical results. Three months postoperatively no statistical difference in intraocular pressure (loose closure 15.1 +/- 3.3 mm Hg, tight closure 15.0 +/- 3.6 mm Hg, p > 0.05) or number of glaucoma medicines (loose closure 1.6, tight closure 1.3, p > 0.05) existed between treatment groups. In the early postoperative period, no statistical difference between groups was observed in the anterior chamber depth, visual acuity or intraocular pressure (p > 0.05). Laser suture lysis was performed without complication in nine patients with a statistically significant reduction in intraocular pressure (p < 0.01). This study suggests, by the technique used, that no obvious benefit exists in using a tight versus a loose scleral flap closure when performing a trabeculectomy.

RCT Entities:   Population Interventions Outcomes