K M Sittig1, E A Deitch. 1. Department of Surgery Louisiana State University Medical Center, Shreveport 71130-3932.
Abstract
BACKGROUND: Because of the inherent risks of blood transfusions, including the transmission of viral and other infectious diseases, it is important to re-evaluate blood transfusion policies. METHODS: The present study compared the results of a new selective transfusion policy in which patients were not transfused unless their hemoglobin levels went below 6-6.5 g/dL versus our previous routine transfusion policy in which the hemoglobin levels were routinely maintained at 10 g/dL. The selectively transfused group consisted of 14 patients with a mean +/- SD burn size of 28% +/- 11%, while the routinely transfused group consisted of 38 clinically comparable patients with a mean burn size of 26% +/- 12%. RESULTS: The patients managed by selective transfusion received fewer transfusions (2.1 +/- 1.7 units) during their hospital stay than patients transfused routinely (7.4 +/- 7.6 units) (p < 0.007) and were less likely to receive maintenance transfusions (4 of 29 total units versus 116 of 282 total units) (p < 0.004). No adverse hemodynamic or other adverse effects related to limiting blood transfusions in the selectively transfused group was noted. CONCLUSION: Routinely transfused patients, on average, received over 5 units more blood than the selective group without any apparent clinical benefit. Thus, the results of this pilot study support a policy of selective blood transfusions in burn patients.
BACKGROUND: Because of the inherent risks of blood transfusions, including the transmission of viral and other infectious diseases, it is important to re-evaluate blood transfusion policies. METHODS: The present study compared the results of a new selective transfusion policy in which patients were not transfused unless their hemoglobin levels went below 6-6.5 g/dL versus our previous routine transfusion policy in which the hemoglobin levels were routinely maintained at 10 g/dL. The selectively transfused group consisted of 14 patients with a mean +/- SD burn size of 28% +/- 11%, while the routinely transfused group consisted of 38 clinically comparable patients with a mean burn size of 26% +/- 12%. RESULTS: The patients managed by selective transfusion received fewer transfusions (2.1 +/- 1.7 units) during their hospital stay than patients transfused routinely (7.4 +/- 7.6 units) (p < 0.007) and were less likely to receive maintenance transfusions (4 of 29 total units versus 116 of 282 total units) (p < 0.004). No adverse hemodynamic or other adverse effects related to limiting blood transfusions in the selectively transfused group was noted. CONCLUSION: Routinely transfused patients, on average, received over 5 units more blood than the selective group without any apparent clinical benefit. Thus, the results of this pilot study support a policy of selective blood transfusions in burn patients.
Authors: Tina L Palmieri; James H Holmes; Brett Arnoldo; Michael Peck; Bruce Potenza; Amalia Cochran; Booker T King; William Dominic; Robert Cartotto; Dhaval Bhavsar; Nathan Kemalyan; Edward Tredget; Francois Stapelberg; David Mozingo; Bruce Friedman; David G Greenhalgh; Sandra L Taylor; Brad H Pollock Journal: Ann Surg Date: 2017-10 Impact factor: 12.969
Authors: R D Glatter; J S Goldberg; K T Schomacker; C C Compton; T J Flotte; D P Bua; K W Greaves; N S Nishioka; R L Sheridan Journal: Ann Surg Date: 1998-08 Impact factor: 12.969