Literature DB >> 8144902

Complement inhibitor of rat cell membrane resembling mouse Crry/p65.

H Takizawa1, N Okada, H Okada.   

Abstract

Neuraminidase-treated rat erythrocytes are resistant to homologous rat C although they are readily hemolyzed by heterologous serum C via the alternative pathway. We established a mAb, mAb512, which allows for hemolysis of neuraminidase-treated rat erythrocytes by homologous rat serum. mAb512 detected rat erythrocyte membrane components with molecular masses of 65 kDa and 55 kDa by Western blotting analysis. Furthermore, mAb512 caused C3b deposition on rat myeloma cells after treatment with rat serum. 512Ag was purified by use of an immunosorbent column prepared with mAb512. Partial sequencing of 512Ag peptides showed significant homology to mouse Crry/p65 indicating that 512Ag could be the rat counterpart of mouse Crry/p65.

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Year:  1994        PMID： 8144902

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  22 in total

1.  Tissue distribution of products of the mouse decay-accelerating factor (DAF) genes. Exploitation of a Daf1 knock-out mouse and site-specific monoclonal antibodies.

Authors:  F Lin; Y Fukuoka; A Spicer; R Ohta; N Okada; C L Harris; S N Emancipator; M E Medof
Journal:  Immunology       Date:  2001-10       Impact factor: 7.397

2.  Tissue distribution of the rat analogue of decay-accelerating factor.

Authors:  O B Spiller; S M Hanna; B P Morgan
Journal:  Immunology       Date:  1999-07       Impact factor: 7.397

3.  A monoclonal antibody to the rat Crry/p65 antigen, a complement regulatory membrane protein, stimulates adhesion and proliferation of thymocytes.

Authors:  N Arsenović-Ranin; D Vucević; N Okada; M Dimitrijević; M Colić
Journal:  Immunology       Date:  2000-07       Impact factor: 7.397

4.  Expression and function of membrane regulators of complement on rat astrocytes in culture.

Authors:  C A Rogers; P Gasque; S J Piddlesden; N Okada; V M Holers; B P Morgan
Journal:  Immunology       Date:  1996-05       Impact factor: 7.397

Review 5.  The role of complement system in ocular diseases including uveitis and macular degeneration.

Authors:  Purushottam Jha; Puran S Bora; Nalini S Bora
Journal:  Mol Immunol       Date:  2007-09       Impact factor: 4.407

6.  Tubulointerstitial injury induced in rats by a monoclonal antibody that inhibits function of a membrane inhibitor of complement.

Authors:  A Nomura; K Nishikawa; Y Yuzawa; H Okada; N Okada; B P Morgan; S J Piddlesden; M Nadai; T Hasegawa; S Matsuo
Journal:  J Clin Invest       Date:  1995-11       Impact factor: 14.808

7.  Molecular characterization of rat Crry: widespread distribution of two alternative forms of Crry mRNA.

Authors:  R J Quigg; C F Lo; J J Alexander; A E Sneed; G Moxley
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

8.  Tissue distribution of the guinea-pig decay-accelerating factor.

Authors:  K Nishikawa; S Matsuo; H Tamai; N Okada; H Okada
Journal:  Immunology       Date:  1998-10       Impact factor: 7.397

9.  Membrane-bound complement regulatory activity is decreased on vaccinia virus-infected cells.

Authors:  L Baranyi; N Okada; K Baranji; H Takizawa; H Okada
Journal:  Clin Exp Immunol       Date:  1994-10       Impact factor: 4.330

10.  Cell-surface bound complement regulatory activity is necessary for the in vivo survival of KDH-8 rat hepatoma.

Authors:  L Baranyi; K Baranji; H Takizawa; N Okada; H Okada
Journal:  Immunology       Date:  1994-08       Impact factor: 7.397
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