| Literature DB >> 9824490 |
K Nishikawa1, S Matsuo, H Tamai, N Okada, H Okada.
Abstract
MCA44 is a monoclonal antibody (mAb) to guinea-pig decay-accelerating factor (DAF) and, using this mAb, tissue distribution of guinea-pig DAF was studied by immunofluorescence. Guinea-pig DAF was found to be expressed not only on the vascular endothelium but also on different types of cells, such as the tubular epithelium of the kidney, epidermal cells of the skin and synovial lining cells. As there was no significant reduction in staining intensity with MCA44 following treatment with phosphatidylinositol-specific phospholipase C, many guinea-pig DAF molecules expressed in these tissues may be of the transmembrane form.Entities:
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Year: 1998 PMID: 9824490 PMCID: PMC1364319 DOI: 10.1046/j.1365-2567.1998.00592.x
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397