Literature DB >> 8144235

High exposures to organic solvents among graffiti removers.

H Anundi1, M L Lind, L Friis, N Itkes, S Langworth, C Edling.   

Abstract

The exposure to organic solvents among 12 graffiti removers was studied. Health effects were also assessed by structured interview and a symptom questionnaire. Blood and urine samples were collected at the end of the day of air sampling. The concentrations of dichloromethane, glycol ethers, trimethylbenzenes and N-methyl-2-pyrrolidinone in the breathing zone of each worker were measured during one working day. The 8-h time-weighted average exposure to dichloromethane ranged from 18 to 1200 mg/m3. The Swedish Permissible Exposure Limit value for dichloromethane is 120 mg/m3. The air concentrations of glycol ethers, trimethylbenzenes and N-methyl-2-pyrrolidinone were low or not detectable. No exposure-related deviations in the serum concentrations of creatinine, aspartate transaminase, alanine transaminase, gamma-glutamyl transpeptidase or hyaluronan or the urine concentrations of alpha 1-microglobulin, beta 2-microglobulin or N-acetyl-beta-glucosaminidase were found. Irritative symptoms of the eyes and upper respiratory tract were more prevalent than in the general population. This study demonstrates that old knowledge about work hazards is not automatically transferred to new professions. Another aspect is that the public is also exposed as the job is performed during daytime in underground stations. At least for short periods, bystanders may be exposed to high concentrations of organic solvent vapours. People with predisposing conditions, e.g. asthmatics, may risk adverse reactions.

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Year:  1993        PMID: 8144235     DOI: 10.1007/bf00381198

Source DB:  PubMed          Journal:  Int Arch Occup Environ Health        ISSN: 0340-0131            Impact factor:   3.015


  15 in total

1.  Studies on methylene chloride-induced fatty liver.

Authors:  J B Morris; F A Smith; R H Garman
Journal:  Exp Mol Pathol       Date:  1979-06       Impact factor: 3.362

2.  Some organic solvents, resin monomers and related compounds, pigments and occupational exposures in paint manufacture and painting.

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Journal:  IARC Monogr Eval Carcinog Risks Hum       Date:  1989

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Authors:  S MOSKOWITZ; H SHAPIRO
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Journal:  Am Ind Hyg Assoc J       Date:  1969 Sep-Oct

5.  Metabolism of dihalomethanes to carbon monoxide. I. In vivo studies.

Authors:  V L Kubic; M W Anders; R R Engel; C H Barlow; W S Caughey
Journal:  Drug Metab Dispos       Date:  1974 Jan-Feb       Impact factor: 3.922

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Authors:  C L Winek; W D Collom; F Esposito
Journal:  Forensic Sci Int       Date:  1981 Sep-Oct       Impact factor: 2.395

7.  Pulmonary reactions to inhalation of methylene chloride: effects on lipid peroxidation in rats.

Authors:  S C Sahu; D K Lowther
Journal:  Toxicol Lett       Date:  1981 Jun-Jul       Impact factor: 4.372

8.  Environmental, occupational, and personal factors related to the prevalence of sick building syndrome in the general population.

Authors:  D Norbäck; C Edling
Journal:  Br J Ind Med       Date:  1991-07

9.  Absorption through human skin of ibuprofen and flurbiprofen; effect of dose variation, deposited drug films, occlusion and the penetration enhancer N-methyl-2-pyrrolidone.

Authors:  S A Akhter; B W Barry
Journal:  J Pharm Pharmacol       Date:  1985-01       Impact factor: 3.765

10.  Methylene chloride inhalation: an unusual form of drug abuse.

Authors:  K Sturmann; H Mofenson; T Caraccio
Journal:  Ann Emerg Med       Date:  1985-09       Impact factor: 5.721

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  6 in total

1.  Field survey on types of organic solvents used in enterprises of various sizes.

Authors:  Hajime Samoto; Yoshinari Fukui; Hirohiko Ukai; Satoru Okamoto; Shiro Takada; Fumiko Ohashi; Jiro Moriguchi; Takafumi Ezaki; Masayuki Ikeda
Journal:  Int Arch Occup Environ Health       Date:  2006-03-14       Impact factor: 3.015

2.  Ambient monitoring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility.

Authors:  Michael Bader; Wolfgang Rosenberger; Thomas Rebe; Stephen A Keener; Thomas H Brock; Hans-Jürgen Hemmerling; Renate Wrbitzky
Journal:  Int Arch Occup Environ Health       Date:  2005-12-15       Impact factor: 3.015

3.  Human volunteer study on the influence of exposure duration and dilution of dermally applied N-methyl-2-pyrrolidone (NMP) on the urinary elimination of NMP metabolites.

Authors:  Stephen A Keener; Renate Wrbitzky; Michael Bader
Journal:  Int Arch Occup Environ Health       Date:  2006-08-09       Impact factor: 3.015

4.  Dermal absorption and urinary elimination of N-methyl-2-pyrrolidone.

Authors:  Michael Bader; Stephen A Keener; Renate Wrbitzky
Journal:  Int Arch Occup Environ Health       Date:  2005-10-12       Impact factor: 3.015

5.  Volatile organic compounds enhance allergic airway inflammation in an experimental mouse model.

Authors:  Ulrike Bönisch; Alexander Böhme; Tibor Kohajda; Iljana Mögel; Nicole Schütze; Martin von Bergen; Jan C Simon; Irina Lehmann; Tobias Polte
Journal:  PLoS One       Date:  2012-07-03       Impact factor: 3.240

6.  Methylene chloride poisoning in a cabinet worker.

Authors:  M Mahmud; S N Kales
Journal:  Environ Health Perspect       Date:  1999-09       Impact factor: 9.031

  6 in total

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