Literature DB >> 8143623

A perspective on nonmutagenic mechanisms in carcinogenesis.

R W Tennant1.   

Abstract

Although there is compelling evidence for multiple mutagenic events in the induction of cancers, there is also substantial evidence in support of nonmutagenic mechanisms. It is proposed that the genetic basis of noninduced or spontaneous tumors, as well as cancers induced by nonmutagens, involves heritable changes in the regulation of gene expression.

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Year:  1993        PMID： 8143623      PMCID： PMC1521175          DOI： 10.1289/ehp.93101s3231

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN： 0091-6765            Impact factor:   9.031


  19 in total

1.  Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators.

Authors:  I Issemann; S Green
Journal:  Nature       Date:  1990-10-18       Impact factor: 49.962

Review 2.  A genetic model for colorectal tumorigenesis.

Authors:  E R Fearon; B Vogelstein
Journal:  Cell       Date:  1990-06-01       Impact factor: 41.582

Review 3.  Too many rodent carcinogens: mitogenesis increases mutagenesis.

Authors:  B N Ames; L S Gold
Journal:  Science       Date:  1990-08-31       Impact factor: 47.728

Review 4.  Endogenous carcinogenesis: molecular oncology into the twenty-first century--presidential address.

Authors:  L A Loeb
Journal:  Cancer Res       Date:  1989-10-15       Impact factor: 12.701

5.  Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist.

Authors:  K Damm; C C Thompson; R M Evans
Journal:  Nature       Date:  1989-06-22       Impact factor: 49.962

6.  Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment.

Authors:  S H Reynolds; S J Stowers; R M Patterson; R R Maronpot; S A Aaronson; M W Anderson
Journal:  Science       Date:  1987-09-11       Impact factor: 47.728

7.  Neoplasms observed in untreated and corn oil gavage control groups of F344/N rats and (C57BL/6N X C3H/HeN)F1 (B6C3F1) mice.

Authors:  J K Haseman; J E Huff; G N Rao; J E Arnold; G A Boorman; E E McConnell
Journal:  J Natl Cancer Inst       Date:  1985-11       Impact factor: 13.506

8.  Spontaneous cancer and its possible relationship to oxygen metabolism.

Authors:  J R Totter
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

9.  Effects of corn oil, time-related changes, and inter-laboratory variability on tumor occurrence in control Fischer 344 (F344/N) rats.

Authors:  J K Haseman; G N Rao
Journal:  Toxicol Pathol       Date:  1992       Impact factor: 1.902

10.  Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice.

Authors:  N R Drinkwater; J J Ginsler
Journal:  Carcinogenesis       Date:  1986-10       Impact factor: 4.944
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  3 in total

Review 1.  A new hypothesis for the cancer mechanism.

Authors:  Xiaolong Meng; Jie Zhong; Shuying Liu; Mollianne Murray; Ana M Gonzalez-Angulo
Journal:  Cancer Metastasis Rev       Date:  2012-06       Impact factor: 9.264

Review 2.  Cell cycle control, checkpoint mechanisms, and genotoxic stress.

Authors:  R E Shackelford; W K Kaufmann; R S Paules
Journal:  Environ Health Perspect       Date:  1999-02       Impact factor: 9.031

3.  A metabolomics investigation of non-genotoxic carcinogenicity in the rat.

Authors:  Zsuzsanna Ament; Claire L Waterman; James A West; Catherine Waterfield; Richard A Currie; Jayne Wright; Julian L Griffin
Journal:  J Proteome Res       Date:  2013-11-07       Impact factor: 4.466
  3 in total

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