Literature DB >> 2129546

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators.

I Issemann1, S Green.   

Abstract

We have cloned a member of the steroid hormone receptor superfamily of ligand-activated transcription factors. The receptor homologue is activated by a diverse class of rodent hepatocarcinogens that causes proliferation of peroxisomes. Identification of a peroxisome proliferator-activated receptor should help elucidate the mechanism of the hypolipidaemic effect of these hepatocarcinogens and aid evaluation of their potential carcinogenic risk to man.

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Year:  1990        PMID： 2129546     DOI： 10.1038/347645a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  762 in total

1.  Stress induces peroxisome biogenesis genes.

Authors:  E Lopez-Huertas; W L Charlton; B Johnson; I A Graham; A Baker
Journal:  EMBO J       Date:  2000-12-15       Impact factor: 11.598

2.  Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I.

Authors:  G Martin; H Duez; C Blanquart; V Berezowski; P Poulain; J C Fruchart; J Najib-Fruchart; C Glineur; B Staels
Journal:  J Clin Invest       Date:  2001-06       Impact factor: 14.808

Review 3.  Peroxisome proliferator-activated receptors: lipid binding proteins controling gene expression.

Authors:  Marc van Bilsen; Ger J van der Vusse; Andries J Gilde; Martijn Lindhout; Karin A J M van der Lee
Journal:  Mol Cell Biochem       Date:  2002-10       Impact factor: 3.396

4.  Peroxisome proliferator-activated receptor γ inhibits pulmonary hypertension targeting store-operated calcium entry.

Authors:  Yingfeng Wang; Wenju Lu; Kai Yang; Yan Wang; Jie Zhang; Jing Jia; Xin Yun; Lichun Tian; Yuqin Chen; Qian Jiang; Bo Zhang; Xiuqing Chen; Jian Wang
Journal:  J Mol Med (Berl)       Date:  2014-11-14       Impact factor: 4.599

Review 5.  PPARgamma as a potential therapeutic target in pulmonary hypertension.

Authors:  Roy L Sutliff; Bum-Yong Kang; C Michael Hart
Journal:  Ther Adv Respir Dis       Date:  2010-06       Impact factor: 4.031

6.  Repression of cytochrome P450 by cytokines: IL-1 beta counteracts clofibric acid induction of CYP4A in cultured fetal rat hepatocytes.

Authors:  J H Parmentier; P Kremers; L Ferrari; A M Batt; J E Gielen; G Siest
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Review 7.  The Roles of Xenobiotic Receptors: Beyond Chemical Disposition.

Authors:  Bryan Mackowiak; Jessica Hodge; Sydney Stern; Hongbing Wang
Journal:  Drug Metab Dispos       Date:  2018-05-14       Impact factor: 3.922

8.  Peroxisome proliferator-activated receptor-γ agonist-mediated inhibition of cell growth is independent of apoptosis in human epidermoid carcinoma A431 cells.

Authors:  Qian Li; Yu-Sheng Peng; Ping-Jiao Chen; Meng-Lei Wang; Can Cao; Hao Xiong; Jing Zhang; Ming-Hua Chen; Xue-Biao Peng; Kang Zeng
Journal:  Oncol Lett       Date:  2018-02-28       Impact factor: 2.967

9.  Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor alpha-regulated gene expression.

Authors:  C Qi; Y Zhu; J Pan; A V Yeldandi; M S Rao; N Maeda; V Subbarao; S Pulikuri; T Hashimoto; J K Reddy
Journal:  Proc Natl Acad Sci U S A       Date:  1999-02-16       Impact factor: 11.205

Review 10.  Genetic-dependency of peroxisomal cell functions - emerging aspects.

Authors:  N Latruffe; J Vamecq; M Cherkaoui Malki
Journal:  J Cell Mol Med       Date:  2003 Jul-Sep       Impact factor: 5.310
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