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Literature DB >> 8143121

Protease-dependent virus tropism and pathogenicity.

Abstract

Viral tissue tropism in a susceptible host is often determined by virus-receptor interactions. Nevertheless, closely related viruses utilizing the same receptor molecules can display striking differences in tropism, or a virus can cause a localized infection despite the widespread occurrence of the receptor. These events are now explained by another mechanism of tropism, in which host proteases play a major role by activating viral fusion glycoproteins.

Entities: Disease

Mesh：

Substances：

Year: 1993 PMID： 8143121 PMCID： PMC7133224 DOI： 10.1016/0966-842x(93)90112-5

Source DB: PubMed Journal: Trends Microbiol ISSN： 0966-842X Impact factor: 17.079

63 in total

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Authors: P J Barr
Journal: Cell Date: 1991-07-12 Impact factor: 41.582

2. Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells.

Authors: Y Kawaoka; R G Webster
Journal: Proc Natl Acad Sci U S A Date: 1988-01 Impact factor: 11.205

3. Functional expression of furin demonstrating its intracellular localization and endoprotease activity for processing of proalbumin and complement pro-C3.

Authors: Y Misumi; K Oda; T Fujiwara; N Takami; K Tashiro; Y Ikehara
Journal: J Biol Chem Date: 1991-09-05 Impact factor: 5.157

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Authors: W Schuy; W Garten; D Linder; H D Klenk
Journal: Virus Res Date: 1984 Impact factor: 3.303

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Authors: M Tashiro; P Ciborowski; H D Klenk; G Pulverer; R Rott
Journal: Nature Date: 1987 Feb 5-11 Impact factor: 49.962

6. Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus.

Authors: J M McCune; L B Rabin; M B Feinberg; M Lieberman; J C Kosek; G R Reyes; I L Weissman
Journal: Cell Date: 1988-04-08 Impact factor: 41.582

7. Is virulence of H5N2 influenza viruses in chickens associated with loss of carbohydrate from the hemagglutinin?

Authors: Y Kawaoka; C W Naeve; R G Webster
Journal: Virology Date: 1984-12 Impact factor: 3.616

8. Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of Avian influenza viruses.

Authors: F X Bosch; W Garten; H D Klenk; R Rott
Journal: Virology Date: 1981-09 Impact factor: 3.616

9. Expression of factor X and its significance for the determination of paramyxovirus tropism in the chick embryo.

Authors: T Ogasawara; B Gotoh; H Suzuki; J Asaka; K Shimokata; R Rott; Y Nagai
Journal: EMBO J Date: 1992-02 Impact factor: 11.598

10. Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R.

Authors: M Vey; M Orlich; S Adler; H D Klenk; R Rott; W Garten
Journal: Virology Date: 1992-05 Impact factor: 3.616

25 in total

1. Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infection.

Authors: Rebecca M Richards; Douglas R Lowy; John T Schiller; Patricia M Day
Journal: Proc Natl Acad Sci U S A Date: 2006-01-23 Impact factor: 11.205

2. Cleavage of influenza A virus H1 hemagglutinin by swine respiratory bacterial proteases.

Authors: R J Callan; F A Hartmann; S E West; V S Hinshaw
Journal: J Virol Date: 1997-10 Impact factor: 5.103

3. Transfection of Sendai virus F gene cDNA with mutations at its cleavage site and HN gene cDNA into COS cells induces cell fusion.

Authors: H Taira; T Sato; H Segawa; M Chiba; T Katsumata; K Iwasaki
Journal: Arch Virol Date: 1995 Impact factor: 2.574

4. Positive and negative host factors for Sendai virus transcription and their organ distribution in rat.

Authors: T Takagi; M Iwama; K Seta; T Kanda; T Tsukamoto; S Tominaga; K Mizumoto
Journal: Arch Virol Date: 1996 Impact factor: 2.574

5. Deduced amino acid sequences surrounding the fusion glycoprotein cleavage site and of the carboxyl-terminus of haemagglutinin-neuraminidase protein of the avirulent thermostable vaccine strain I-2 of Newcastle disease virus.

Authors: P N Wambura; J Meers; J A Kattenbelt; A R Gould; P B Spradbrow
Journal: Vet Res Commun Date: 2006-12-29 Impact factor: 2.459

6. Characterization of an alternate form of Newcastle disease virus fusion protein.

Authors: Homer Pantua; Lori W McGinnes; John Leszyk; Trudy G Morrison
Journal: J Virol Date: 2005-09 Impact factor: 5.103

7. A furin-defective cell line is able to process correctly the gp160 of human immunodeficiency virus type 1.

Authors: Y Ohnishi; T Shioda; K Nakayama; S Iwata; B Gotoh; M Hamaguchi; Y Nagai
Journal: J Virol Date: 1994-06 Impact factor: 5.103

8. Engineered serine protease inhibitor prevents furin-catalyzed activation of the fusion glycoprotein and production of infectious measles virus.

Authors: M Watanabe; A Hirano; S Stenglein; J Nelson; G Thomas; T C Wong
Journal: J Virol Date: 1995-05 Impact factor: 5.103

9. Protease-induced infectivity of hepatitis B virus for a human hepatoblastoma cell line.

Authors: X Lu; T M Block; W H Gerlich
Journal: J Virol Date: 1996-04 Impact factor: 5.103

10. Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro.

Authors: Yiu-Wing Kam; Yuushi Okumura; Hiroshi Kido; Lisa F P Ng; Roberto Bruzzone; Ralf Altmeyer
Journal: PLoS One Date: 2009-11-17 Impact factor: 3.240