Literature DB >> 8132813

Impact of rotavirus infection on a paediatric hospital in the east end of London.

J S Noel1, S P Parker, K Choules, A D Phillips, J Walker-Smith, W D Cubitt.   

Abstract

AIMS: To study the impact of confirmed rotavirus infection at a paediatric hospital; to use the data to obtain a minimum estimate of the cost of treating reported cases of rotavirus in England and Wales.
METHODS: Data were obtained on all patients with rotavirus over a two year period. Information was collected on 386 patients with rotavirus infection who were treated at the 120 bed Queen Elizabeth Hospital for Children in East London. This included the virus serotype, the patient's age, whether they required intravenous infusion, duration of hospital stay, numbers of patients treated in the casualty department, and numbers who had to be admitted. Treatment costs were obtained from the Finance Department of the Hospitals for Sick Children.
RESULTS: The minimum cost of treating patients, excluding the cost of medical staff at the hospital, was estimated to be 95,400 pounds a year. One hundred and forty eight (38%) patients were admitted to the wards and a further 49 patients developed symptoms while in hospital. Intravenous infusion was required by 18 patients. The mean duration of hospital stay was 5.5 days. One hundred and eighty nine (49%) patients were treated with oral rehydration solution in casualty, given advice, and sent home. Ninety four per cent of the patients were aged under 2 years. The findings were comparable with those obtained in a study at Texas Children's Hospital, USA. The G serotype (VP7) of rotavirus did not influence the severity of infection.
CONCLUSION: Rotavirus infections accounted for a significant number of patients treated in casualty, admissions to hospital, and bed occupancy in a paediatric hospital. The estimated cost of treating reported cases of rotavirus in England and Wales is in excess of 6.3 pounds million a year.

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Mesh:

Year:  1994        PMID: 8132813      PMCID: PMC501760          DOI: 10.1136/jcp.47.1.67

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  3 in total

1.  Simple and specific enzyme immunoassay using monoclonal antibodies for serotyping human rotaviruses.

Authors:  B S Coulson; L E Unicomb; G A Pitson; R F Bishop
Journal:  J Clin Microbiol       Date:  1987-03       Impact factor: 5.948

2.  Impact of rotavirus infection at a large pediatric hospital.

Authors:  D O Matson; M K Estes
Journal:  J Infect Dis       Date:  1990-09       Impact factor: 5.226

3.  Epidemiological survey of human rotavirus serotypes and electropherotypes in young children admitted to two children's hospitals in northeast London from 1984 to 1990.

Authors:  J S Noel; G M Beards; W D Cubitt
Journal:  J Clin Microbiol       Date:  1991-10       Impact factor: 5.948

  3 in total
  11 in total

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Authors:  M I Gómara; D Cubitt; U Desselberger; J Gray
Journal:  J Clin Microbiol       Date:  2001-10       Impact factor: 5.948

2.  Intussusception and the great smog of London, December 1952.

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Review 3.  The paediatric burden of rotavirus disease in Europe.

Authors: 
Journal:  Epidemiol Infect       Date:  2006-04-04       Impact factor: 2.451

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Authors:  P K Lorgelly; D Joshi; M Iturriza Gómara; J Gray; M Mugford
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5.  Etiology of acute gastroenteritis in hospitalized children in Melbourne, Australia, from April 1980 to March 1993.

Authors:  G L Barnes; E Uren; K B Stevens; R F Bishop
Journal:  J Clin Microbiol       Date:  1998-01       Impact factor: 5.948

6.  Infantile gastroenteritis in the community: a cost-of-illness study.

Authors:  P K Lorgelly; D Joshi; M Iturriza Gómara; C Flood; C A Hughes; J Dalrymple; J Gray; M Mugford
Journal:  Epidemiol Infect       Date:  2007-03-05       Impact factor: 2.451

7.  Rotavirus outbreak in central Australia.

Authors:  Ged Williams; Linda Zerna
Journal:  Aust Infect Control       Date:  2016-03-17

8.  Rotavirus infection in hospitalised children: incidence and impact on healthcare resources.

Authors:  M Harrington; K Butler; M Cafferkey
Journal:  Ir J Med Sci       Date:  2003 Jan-Mar       Impact factor: 1.568

9.  Budget impact analysis of universal rotavirus vaccination in the Local Health Unit 11 Empoli, Tuscany, Italy.

Authors:  S Guarducci; C Lorini; M Balli; M Donzellini; P Filidei; E Mugnaini; A Silva; G Mazzoni; G Bonaccorsi; P Bonanni; S Boccalini
Journal:  J Prev Med Hyg       Date:  2015-08-05

10.  Economic Cost of Campylobacter, Norovirus and Rotavirus Disease in the United Kingdom.

Authors:  Clarence C Tam; Sarah J O'Brien
Journal:  PLoS One       Date:  2016-02-01       Impact factor: 3.240

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