Literature DB >> 8132485

Dialectics in carrier research: the ADP/ATP carrier and the uncoupling protein.

M Klingenberg1.   

Abstract

A concise review is given of the research in our laboratory on the ADP/ATP carrier (AAC) and the uncoupling protein (UCP). Although homologous proteins, their widely different functions and contrasts are stressed. The pioneer role of research on the AAC, not only for the mitochondrial but also for other carriers, and the present state of their structure-function relationship is reviewed. The function of UCP as a highly regulated H+ carrier is described in contrast to the largely unregulated ADP/ATP exchange in AAC. General principles of carrier catalysis as derived from studies on the AAC and UCP are elucidated.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8132485     DOI： 10.1007/bf01108402

Source DB:  PubMed          Journal:  J Bioenerg Biomembr        ISSN： 0145-479X            Impact factor:   2.945


  56 in total

Review 1.  Structure-function of the ADP/ATP carrier.

Authors:  M Klingenberg
Journal:  Biochem Soc Trans       Date:  1992-08       Impact factor: 5.407

2.  Hunting for the pore of voltage-gated channels.

Authors:  C Miller; H Hughes
Journal:  Curr Biol       Date:  1992-11       Impact factor: 10.834

3.  Electrical imbalance of adenine nucleotide transport across the mitochondrial membrane.

Authors:  K LaNoue; S M Mizani; M Klingenberg
Journal:  J Biol Chem       Date:  1978-01-10       Impact factor: 5.157

Review 4.  Principles of carrier catalysis elucidated by comparing two similar membrane translocators from mitochondria, the ADP/ATP carrier and the uncoupling protein.

Authors:  M Klingenberg
Journal:  Ann N Y Acad Sci       Date:  1985       Impact factor: 5.691

5.  Effect of bongkrekic acid on the adenine nucleotide carrier in mitochondria: tightening of adenine nucleotide binding and differentiation between inner and outer sites.

Authors:  M J Weidemann; H Erdelt; M Klingenberg
Journal:  Biochem Biophys Res Commun       Date:  1970-05-11       Impact factor: 3.575

6.  Unspecific permeation and specific exchange of adenine nucleotides in liver mitochondria.

Authors:  E Pfaff; M Klingenberg; H W Heldt
Journal:  Biochim Biophys Acta       Date:  1965-06-15

Review 7.  The utilization of binding energy in coupled vectorial processes.

Authors:  W P Jencks
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1980

8.  Electrophoretic control of reconstituted adenine nucleotide translocation.

Authors:  R Krämer; M Klingenberg
Journal:  Biochemistry       Date:  1982-03-02       Impact factor: 3.162

9.  Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. Isolation and analysis of AAC2.

Authors:  J E Lawson; M G Douglas
Journal:  J Biol Chem       Date:  1988-10-15       Impact factor: 5.157

10.  Structure-function studies of adenine nucleotide transport in mitochondria. I. Construction and genetic analysis of yeast mutants encoding the ADP/ATP carrier protein of mitochondria.

Authors:  J E Lawson; M Gawaz; M Klingenberg; M G Douglas
Journal:  J Biol Chem       Date:  1990-08-25       Impact factor: 5.157
View more
  12 in total

1.  Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria.

Authors:  Ran Zalk; Adrian Israelson; Erez S Garty; Heftsi Azoulay-Zohar; Varda Shoshan-Barmatz
Journal:  Biochem J       Date:  2005-02-15       Impact factor: 3.857

Review 2.  Electrophysiology of the inner mitochondrial membrane.

Authors:  M Zoratti; I Szabó
Journal:  J Bioenerg Biomembr       Date:  1994-10       Impact factor: 2.945

Review 3.  Oligomeric state and membrane binding behaviour of creatine kinase isoenzymes: implications for cellular function and mitochondrial structure.

Authors:  O Stachowiak; U Schlattner; M Dolder; T Wallimann
Journal:  Mol Cell Biochem       Date:  1998-07       Impact factor: 3.396

4.  Electron tomography of mitochondria from brown adipocytes reveals crista junctions.

Authors:  G A Perkins; J Y Song; L Tarsa; T J Deerinck; M H Ellisman; T G Frey
Journal:  J Bioenerg Biomembr       Date:  1998-10       Impact factor: 2.945

5.  Molecular cloning of a peroxisomal Ca2+-dependent member of the mitochondrial carrier superfamily.

Authors:  F E Weber; G Minestrini; J H Dyer; M Werder; D Boffelli; S Compassi; E Wehrli; R M Thomas; G Schulthess; H Hauser
Journal:  Proc Natl Acad Sci U S A       Date:  1997-08-05       Impact factor: 11.205

Review 6.  An introduction to the mitochondrial anion carrier family.

Authors:  P L Pedersen
Journal:  J Bioenerg Biomembr       Date:  1993-10       Impact factor: 2.945

7.  The mitochondrial carnitine carrier protein: cDNA cloning, primary structure and comparison with other mitochondrial transport proteins.

Authors:  C Indiveri; V Iacobazzi; N Giangregorio; F Palmieri
Journal:  Biochem J       Date:  1997-02-01       Impact factor: 3.857

8.  Four mutations in transmembrane domains of the mitochondrial ADP/ATP carrier increase resistance to bongkrekic acid.

Authors:  Igor Zeman; Christine Schwimmer; Vincent Postis; Gérard Brandolin; Claudine David; Véronique Trézéguet; Guy J M Lauquin
Journal:  J Bioenerg Biomembr       Date:  2003-06       Impact factor: 2.945

Review 9.  Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection.

Authors:  Susana Cardoso; Sónia Correia; Cristina Carvalho; Emanuel Candeias; Ana I Plácido; Ana I Duarte; Raquel M Seiça; Paula I Moreira
Journal:  J Bioenerg Biomembr       Date:  2014-09-14       Impact factor: 2.945

Review 10.  The mitochondrial ADP/ATP carrier: functional and structural studies in the route of elucidating pathophysiological aspects.

Authors:  Véronique Trézéguet; Ludovic Pélosi; Guy J M Lauquin; Gérard Brandolin
Journal:  J Bioenerg Biomembr       Date:  2008-11-01       Impact factor: 3.853
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.