Literature DB >> 8130334

Low single channel conductance of the major skeletal muscle chloride channel, ClC-1.

M Pusch1, K Steinmeyer, T J Jentsch.   

Abstract

We expressed the skeletal muscle chloride channel, ClC-1, in HEK293 cells and investigated it with the patch-clamp technique. Macroscopic properties are similar to those obtained after expression in Xenopus oocytes, except that faster gating kinetics are observed in mammalian cells. Nonstationary noise analysis revealed that both rat and human ClC-1 have a low single channel conductance of about 1 pS. This finding may explain the lack of single-channel data for chloride channels from skeletal muscle despite its high macroscopic chloride conductance.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8130334      PMCID： PMC1275674          DOI： 10.1016/S0006-3495(94)80753-2

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  31 in total

1.  The skeletal muscle chloride channel in dominant and recessive human myotonia.

Authors:  M C Koch; K Steinmeyer; C Lorenz; K Ricker; F Wolf; M Otto; B Zoll; F Lehmann-Horn; K H Grzeschik; T J Jentsch
Journal:  Science       Date:  1992-08-07       Impact factor: 47.728

2.  Nonstationary noise analysis and application to patch clamp recordings.

Authors:  S H Heinemann; F Conti
Journal:  Methods Enzymol       Date:  1992       Impact factor: 1.600

3.  Characterization of ion channels on the surface membrane of adult rat skeletal muscle.

Authors:  M Chua; W J Betz
Journal:  Biophys J       Date:  1991-06       Impact factor: 4.033

4.  Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel.

Authors:  K Steinmeyer; C Ortland; T J Jentsch
Journal:  Nature       Date:  1991-11-28       Impact factor: 49.962

5.  Completely functional double-barreled chloride channel expressed from a single Torpedo cDNA.

Authors:  C K Bauer; K Steinmeyer; J R Schwarz; T J Jentsch
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

6.  Effects of denervation and colchicine treatment on the chloride conductance of rat skeletal muscle fibers.

Authors:  D Camerino; S H Bryant
Journal:  J Neurobiol       Date:  1976-05

7.  Chloride channels with reduced single-channel conductance in recessive myotonia congenita.

Authors:  C Fahlke; E Zachar; R Rüdel
Journal:  Neuron       Date:  1993-02       Impact factor: 17.173

8.  Development of electrical myotonia in the ADR mouse: role of chloride conductance in myotubes and neonatal animals.

Authors:  E Wischmeyer; E Nolte; R Klocke; H Jockusch; H Brinkmeier
Journal:  Neuromuscul Disord       Date:  1993-07       Impact factor: 4.296

9.  Indanyloxyacetic acid-sensitive chloride channels from outer membranes of skeletal muscle.

Authors:  S Weber-Schürholz; E Wischmeyer; M Laurien; H Jockusch; T Schürholz; D W Landry; Q al-Awqati
Journal:  J Biol Chem       Date:  1993-01-05       Impact factor: 5.157

10.  Chloride channels activated by osmotic stress in T lymphocytes.

Authors:  R S Lewis; P E Ross; M D Cahalan
Journal:  J Gen Physiol       Date:  1993-06       Impact factor: 4.086
View more
  55 in total

1.  Modulation of the gating of CIC-1 by S-(-) 2-(4-chlorophenoxy) propionic acid.

Authors:  E C Aromataris; D S Astill; G Y Rychkov; S H Bryant; A H Bretag; M L Roberts
Journal:  Br J Pharmacol       Date:  1999-03       Impact factor: 8.739

2.  Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.

Authors:  J Eggermont; G Buyse; T Voets; J Tytgat; H De Smedt; G Droogmans; B Nilius
Journal:  Biochem J       Date:  1997-07-01       Impact factor: 3.857

3.  Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.

Authors:  G Zifarelli; A Liantonio; A Gradogna; A Picollo; G Gramegna; M De Bellis; A R Murgia; E Babini; D Conte Camerino; M Pusch
Journal:  Br J Pharmacol       Date:  2010-08       Impact factor: 8.739

4.  Mechanism of voltage-dependent gating in skeletal muscle chloride channels.

Authors:  C Fahlke; A Rosenbohm; N Mitrovic; A L George; R Rüdel
Journal:  Biophys J       Date:  1996-08       Impact factor: 4.033

5.  Chloride current in toad skeletal muscle and its modification by the histidine-modifying reagent diethylpyrocarbonate.

Authors:  G C Bertrán; B A Kotsias
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1996-05       Impact factor: 3.000

6.  Molecular basis for decreased muscle chloride conductance in the myotonic goat.

Authors:  C L Beck; C Fahlke; A L George
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

7.  Properties of single-channel and whole cell Cl- currents in guinea pig detrusor smooth muscle cells.

Authors:  Viktor Yarotskyy; John Malysz; Georgi V Petkov
Journal:  Am J Physiol Cell Physiol       Date:  2018-12-19       Impact factor: 4.249

8.  Heteromultimeric CLC chloride channels with novel properties.

Authors:  C Lorenz; M Pusch; T J Jentsch
Journal:  Proc Natl Acad Sci U S A       Date:  1996-11-12       Impact factor: 11.205

9.  Concentration and pH dependence of skeletal muscle chloride channel ClC-1.

Authors:  G Y Rychkov; M Pusch; D S Astill; M L Roberts; T J Jentsch; A H Bretag
Journal:  J Physiol       Date:  1996-12-01       Impact factor: 5.182

10.  Leukoencephalopathy-causing CLCN2 mutations are associated with impaired Cl- channel function and trafficking.

Authors:  Héctor Gaitán-Peñas; Pirjo M Apaja; Tanit Arnedo; Aida Castellanos; Xabier Elorza-Vidal; David Soto; Xavier Gasull; Gergely L Lukacs; Raúl Estévez
Journal:  J Physiol       Date:  2017-10-09       Impact factor: 5.182
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.