Literature DB >> 812696

Determination of the primary structure of a mouse IgG2a immunoglobulin. Amino-acid sequence of the light chain.

C Schiff, M Fougereau.   

Abstract

The amino acid sequence of the light chain of the mouse monoclonal MOPC 173 immunoglobulin molecule (IgG2a,chi) is presented. This kappa chain contains 214 residues. Comparisons of this sequence with murine kappa chains already published by other workers bring a confirmation of the large size of the murine V chi chain pool. A complete identity was found with the constant region of the light chain of MOPC 21 from residue 97 to residue 214.

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Year:  1975        PMID： 812696     DOI： 10.1111/j.1432-1033.1975.tb02479.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN： 0014-2956


  7 in total

1.  Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

Authors:  E E Max; J G Seidman; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1979-07       Impact factor: 11.205

2.  Two rearranged immunoglobulin kappa light chain genes in one mouse myeloma.

Authors:  M Steinmetz; H G Zachau
Journal:  Nucleic Acids Res       Date:  1980-04-25       Impact factor: 16.971

3.  Plasmacytomas with more than one immunoglobulin kappa mRNA: implications for allelic exclusion.

Authors:  O Bernard; N M Gough; J M Adams
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

4.  Complete amino acid sequence of light chain variable regions derived from five monoclonal anti-p-azophenylarsonate antibodies differing with respect to a crossreactive idiotype.

Authors:  M Siegelman; J D Capra
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

5.  Recombined flanks of the variable and joining segments of immunoglobulin genes.

Authors:  J Höchtl; C R Müller; H G Zachau
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

6.  An immunoglobulin light chain from a lupus-prone mouse induces autoantibodies in normal mice.

Authors:  A Puccetti; T Koizumi; P Migliorini; J André-Schwartz; K J Barrett; R S Schwartz
Journal:  J Exp Med       Date:  1990-06-01       Impact factor: 14.307

7.  Amino acid sequence diversity within the family of antibodies bearing the major antiarsonate cross-reactive idiotype of the A strain mouse.

Authors:  C A Slaughter; J D Capra
Journal:  J Exp Med       Date:  1983-11-01       Impact factor: 14.307
  7 in total

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