| Literature DB >> 8125311 |
Abstract
Transactivation of the firefly luciferase-encoding vectors, pXP1 and pXP2, by the alpha isoform of CCAAT/enhancer-binding protein (C/EBP) is reported. Thus, these vectors are not 'promoterless' in every cellular context, and transactivation by C/EBP or a closely related factor should be considered as a possible explanation for the relatively high background levels of luciferase production that are occasionally observed after transfection of certain cells with these or other similar vectors.Entities:
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Year: 1994 PMID: 8125311 DOI: 10.1016/0378-1119(94)90819-2
Source DB: PubMed Journal: Gene ISSN: 0378-1119 Impact factor: 3.688