Literature DB >> 8122308

Site-specific recombinases: tools for genome engineering.

N J Kilby1, M R Snaith, J A Murray.   

Abstract

Site-specific recombinases from bacteriophage and yeasts have been developed as novel tools for manipulating DNA both in the test-tube and in living organisms. We discuss the characteristics of these enzyme systems, review their application in genetic and developmental studies and speculate on their future potential for large-scale directed modifications of eukaryotic genomes.

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Year:  1993        PMID： 8122308     DOI： 10.1016/0168-9525(93)90104-p

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  96 in total

1.  Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro.

Authors:  K Aoki; C Barker; X Danthinne; M J Imperiale; G J Nabel
Journal:  Mol Med       Date:  1999-04       Impact factor: 6.354

2.  Site-specific recombination in mammalian cells expressing the Int recombinase of bacteriophage HK022.

Authors:  M Kolot; N Silberstein; E Yagil
Journal:  Mol Biol Rep       Date:  1999-08       Impact factor: 2.316

3.  A dual reporter screening system identifies the amino acid at position 82 in Flp site-specific recombinase as a determinant for target specificity.

Authors:  Yuri Voziyanov; A Francis Stewart; Makkuni Jayaram
Journal:  Nucleic Acids Res       Date:  2002-04-01       Impact factor: 16.971

4.  Cre-loxP recombination system for large genome rearrangements in Lactococcus lactis.

Authors:  Nathalie Campo; Marie-Line Daveran-Mingot; Kees Leenhouts; Paul Ritzenthaler; Pascal Le Bourgeois
Journal:  Appl Environ Microbiol       Date:  2002-05       Impact factor: 4.792

5.  Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells.

Authors:  Susanne Andreas; Frieder Schwenk; Birgit Küter-Luks; Nicole Faust; Ralf Kühn
Journal:  Nucleic Acids Res       Date:  2002-06-01       Impact factor: 16.971

6.  Non-contact positions impose site selectivity on Cre recombinase.

Authors:  Andreas W Rüfer; Brian Sauer
Journal:  Nucleic Acids Res       Date:  2002-07-01       Impact factor: 16.971

7.  Validation of a self-excising marker in the human pathogen Aspergillus fumigatus by employing the beta-rec/six site-specific recombination system.

Authors:  Thomas Hartmann; Michaela Dümig; Basem M Jaber; Edyta Szewczyk; Patrick Olbermann; Joachim Morschhäuser; Sven Krappmann
Journal:  Appl Environ Microbiol       Date:  2010-07-23       Impact factor: 4.792

8.  T cells develop normally in the absence of both Deltex1 and Deltex2.

Authors:  Sophie M Lehar; Michael J Bevan
Journal:  Mol Cell Biol       Date:  2006-08-21       Impact factor: 4.272

9.  Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice.

Authors:  S M Dymecki
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

10.  Generation and Analysis of Striated Muscle Selective LINC Complex Protein Mutant Mice.

Authors:  Matthew J Stroud; Xi Fang; Jennifer Veevers; Ju Chen
Journal:  Methods Mol Biol       Date:  2018
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