Literature DB >> 8119019

Incidence of posthospitalization proximal deep venous thrombosis after total hip arthroplasty. A pilot study.

A Trowbridge1, C K Boese, B Woodruff, H H Brindley, W E Lowry, T E Spiro.   

Abstract

The incidence of venous thromboembolic disease after hospitalization for elective total hip arthroplasty (THA) was evaluated in a prospective pilot study of 42 patients. Before discharge from the hospital, all patients were free of deep venous thrombosis (DVT) (bilateral lower extremity ascending venography, 38 patients; duplex ultrasonography, two patients; or a combination of both, two patients). After discharge from the hospital, each patient had bilateral duplex ultrasonography and clinical evaluation monthly for three months. Venography was performed when the noninvasive test suggested the presence of DVT. Four (10.5%) of 38 completed patients (95% confidence interval, 4.4-24.8%) developed proximal DVT after hospitalization. Two episodes occurred during the first month after discharge and two during the second month. Three of the four episodes involved the surgically treated extremity. This pilot experience suggests that a significant risk of DVT continues for at least two months after THA. This observation adds support for the emerging clinical trend to continue DVT prophylaxis for at least two months after hospitalization. Further study regarding the incidence of late DVT and its effective prophylaxis seems warranted.

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Year:  1994        PMID: 8119019

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  5 in total

Review 1.  The postdischarge risk of venous thromboembolism after hip replacement. The role of prolonged prophylaxis.

Authors:  D Bergqvist
Journal:  Drugs       Date:  1996       Impact factor: 9.546

2.  Thromboprophylaxis with low molecular weight heparin after major orthopaedic surgery is cost effective.

Authors:  L C Borris; M R Lassen
Journal:  Drugs       Date:  1996       Impact factor: 9.546

Review 3.  Economics of thromboprophylaxis in total hip replacement surgery.

Authors:  J Harrison; D J Warwick; J Coast
Journal:  Pharmacoeconomics       Date:  1997-07       Impact factor: 4.981

Review 4.  Standard or extended-duration prophylaxis in medical patients? A review of the evidence.

Authors:  J E Stark; W J Smith
Journal:  J Thromb Thrombolysis       Date:  2011-10       Impact factor: 2.300

Review 5.  Measuring the outcomes and pharmacoeconomic consequences of venous thromboembolism prophylaxis in major orthopaedic surgery.

Authors:  Sean D Sullivan; Susan R Kahn; Bruce L Davidson; Lars Borris; Patrick Bossuyt; Gary Raskob
Journal:  Pharmacoeconomics       Date:  2003       Impact factor: 4.981

  5 in total

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