Translesional pressure-flow velocity assessment in patients: Part I.

Interventional physiology presents the operator with objective data to facilitate decision making. A thorough and validated understanding of the alterations of pressure and flow in the human coronary circulation is currently in progress. As illustrated in the case studies, some situations have data which may initially appear contradictory or unhelpful to clinical practice. These data should provide a framework to understand the dynamic physiology producing the clinical syndromes in patients undergoing coronary interventional procedures. Future Interventional Physiology Rounds will examine coronary pressure-flow responses during directional atherectomy, stents, and acute myocardial infarction.