Literature DB >> 8114726

Transcription activates RecA-promoted homologous pairing of nucleosomal DNA.

H Kotani1, E B Kmiec.   

Abstract

RecA protein catalyzes the homologous pairing of a single-stranded circular DNA and a linear duplex DNA molecule. When the duplex is packaged into chromatin, formation of homologously paired complexes is blocked. We have established a system for studying the RecA-promoted reaction by using a duplex fragment containing a single-phased nucleosome. Under these conditions there is no reaction leading to formation of joint molecule complexes. However, transcription on the chromatin template activates the formation of complexes. Reaction is dependent on RNA synthesis and DNA sequence homology and proceeds regardless of the direction of transcription.

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Year:  1994        PMID： 8114726      PMCID： PMC358553          DOI： 10.1128/mcb.14.3.1949-1955.1994

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  28 in total

1.  Transcription enhances intrachromosomal homologous recombination in mammalian cells.

Authors:  J A Nickoloff
Journal:  Mol Cell Biol       Date:  1992-12       Impact factor: 4.272

2.  Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones.

Authors:  Y Lorch; J W LaPointe; R D Kornberg
Journal:  Cell       Date:  1987-04-24       Impact factor: 41.582

3.  A bacteriophage RNA polymerase transcribes through a Xenopus 5S RNA gene transcription complex without disrupting it.

Authors:  A P Wolffe; E Jordan; D D Brown
Journal:  Cell       Date:  1986-02-14       Impact factor: 41.582

4.  Kinetic analysis of deoxyribonuclease I cleavages in the nucleosome core: evidence for a DNA superhelix.

Authors:  L C Lutter
Journal:  J Mol Biol       Date:  1978-09-15       Impact factor: 5.469

5.  A simple procedure for parallel sequence analysis of both strands of 5'-labeled DNA.

Authors:  F Razvi; G Gargiulo; A Worcel
Journal:  Gene       Date:  1983-08       Impact factor: 3.688

6.  The role of stable complexes that repress and activate eucaryotic genes.

Authors:  D D Brown
Journal:  Cell       Date:  1984-06       Impact factor: 41.582

7.  DNA bending and its relation to nucleosome positioning.

Authors:  H R Drew; A A Travers
Journal:  J Mol Biol       Date:  1985-12-20       Impact factor: 5.469

8.  Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I.

Authors:  K Voelkel-Meiman; R L Keil; G S Roeder
Journal:  Cell       Date:  1987-03-27       Impact factor: 41.582

9.  Transcriptional activities of mammalian genomes at sites of recombination with foreign DNA.

Authors:  M Schulz; U Freisem-Rabien; R Jessberger; W Doerfler
Journal:  J Virol       Date:  1987-02       Impact factor: 5.103

10.  Structural analysis of a triple complex between the histone octamer, a Xenopus gene for 5S RNA and transcription factor IIIA.

Authors:  D Rhodes
Journal:  EMBO J       Date:  1985-12-16       Impact factor: 11.598
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  14 in total

1.  Position-specific effect of ribonucleotides on the cleavage activity of human topoisomerase II.

Authors:  Y Wang; A Thyssen; O Westergaard; A H Andersen
Journal:  Nucleic Acids Res       Date:  2000-12-15       Impact factor: 16.971

2.  RecA-mediated, targeted mutagenesis in zebrafish.

Authors:  Zongbin Cui; Ying Yang; Christopher D Kaufman; Dritan Agalliu; Perry B Hackett
Journal:  Mar Biotechnol (NY)       Date:  2003 Mar-Apr       Impact factor: 3.619

3.  A role for RNA synthesis in homologous pairing events.

Authors:  H Kotani; E B Kmiec
Journal:  Mol Cell Biol       Date:  1994-09       Impact factor: 4.272

4.  Recognition and alignment of homologous DNA sequences between minichromosomes and single-stranded DNA promoted by RecA protein.

Authors:  J Ramdas; K Muniyappa
Journal:  Mol Gen Genet       Date:  1995-11-27

5.  RNA facilitates RecA-mediated DNA pairing and strand transfer between molecules bearing limited regions of homology.

Authors:  H Kotani; M W Germann; A Andrus; R Vinayak; B Mullah; E B Kmiec
Journal:  Mol Gen Genet       Date:  1996-03-20

6.  Genetic recombination of nucleosomal templates is mediated by transcription.

Authors:  H Kotani; J M Sekiguchi; S Dutta; E B Kmiec
Journal:  Mol Gen Genet       Date:  1994-08-15

7.  DNA cruciforms facilitate in vitro strand transfer on nucleosomal templates.

Authors:  H Kotani; E B Kmiec
Journal:  Mol Gen Genet       Date:  1994-06-15

8.  Targeted insertions of two exogenous collagen genes into both alleles of their endogenous loci in cultured human cells: the insertions are directed by relatively short fragments containing the promoters and the 5' ends of the genes.

Authors:  A Ganguly; S Smelt; R Mewar; A Fertala; A L Sieron; J Overhauser; D J Prockop
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-19       Impact factor: 11.205

9.  The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability.

Authors:  S Chávez; A Aguilera
Journal:  Genes Dev       Date:  1997-12-15       Impact factor: 11.361

10.  A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.

Authors:  J I Piruat; A Aguilera
Journal:  EMBO J       Date:  1998-08-17       Impact factor: 11.598
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