Literature DB >> 8113198

Identification of a genetic locus involved in the biosynthesis of N-acetyl-D-mannosamine, a precursor of the (alpha 2-->8)-linked polysialic acid capsule of serogroup B Neisseria meningitidis.

J S Swartley1, D S Stephens.   

Abstract

We characterized the genetic defect of a capsule-deficient serogroup B meningococcal strain created by Tn916 mutagenesis. The transposon insertion interrupts a capsule biosynthesis gene, synX, which is involved in the production of N-acetyl-D-mannosamine, a precursor of the (alpha 2-->8)-linked polysialic acid capsule of serogroup B meningococci.

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Year:  1994        PMID： 8113198      PMCID： PMC205225          DOI： 10.1128/jb.176.5.1530-1534.1994

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  24 in total

1.  THE SIALIC ACIDS. IV. N-ACYL--D-GLUCOSAMINE 6-PHOSPHATE 2-EPIMERASE.

Authors:  S GHOSH; S ROSEMAN
Journal:  J Biol Chem       Date:  1965-04       Impact factor: 5.157

2.  Biosynthesis of sialic acids by Neisseria meningitidis.

Authors:  R S BLACKLOW; L WARREN
Journal:  J Biol Chem       Date:  1962-11       Impact factor: 5.157

3.  The biosynthesis of cytidine 5'-monophospho-n-acetylneuraminic acid by an enzyme from Neisseria meningitidis.

Authors:  L WARREN; R S BLACKLOW
Journal:  J Biol Chem       Date:  1962-11       Impact factor: 5.157

4.  Antigenic similarities between brain components and bacteria causing meningitis. Implications for vaccine development and pathogenesis.

Authors:  J Finne; M Leinonen; P H Mäkelä
Journal:  Lancet       Date:  1983-08-13       Impact factor: 79.321

5.  Deletions of Tn916-like transposons are implicated in tetM-mediated resistance in pathogenic Neisseria.

Authors:  J S Swartley; C F McAllister; R A Hajjeh; D W Heinrich; D S Stephens
Journal:  Mol Microbiol       Date:  1993-10       Impact factor: 3.501

6.  A comprehensive set of sequence analysis programs for the VAX.

Authors:  J Devereux; P Haeberli; O Smithies
Journal:  Nucleic Acids Res       Date:  1984-01-11       Impact factor: 16.971

7.  Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes.

Authors:  S Hoffman; B C Sorkin; P C White; R Brackenbury; R Mailhammer; U Rutishauser; B A Cunningham; G M Edelman
Journal:  J Biol Chem       Date:  1982-07-10       Impact factor: 5.157

8.  Identification of an inducible catabolic system for sialic acids (nan) in Escherichia coli.

Authors:  E R Vimr; F A Troy
Journal:  J Bacteriol       Date:  1985-11       Impact factor: 3.490

9.  Molecular cloning of the K1 capsular polysaccharide genes of E. coli.

Authors:  R P Silver; C W Finn; W F Vann; W Aaronson; R Schneerson; P J Kretschmer; C F Garon
Journal:  Nature       Date:  1981-02-19       Impact factor: 49.962

10.  Physiology of sialic acid capsular polysaccharide synthesis in serogroup B Neisseria meningitidis.

Authors:  L Masson; B E Holbein
Journal:  J Bacteriol       Date:  1983-05       Impact factor: 3.490
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  21 in total

1.  Genetic basis for biosynthesis of the (alpha 1-->4)-linked N-acetyl-D-glucosamine 1-phosphate capsule of Neisseria meningitidis serogroup X.

Authors:  Yih-Ling Tzeng; Corie Noble; David S Stephens
Journal:  Infect Immun       Date:  2003-12       Impact factor: 3.441

2.  Cationic antimicrobial peptide resistance in Neisseria meningitidis.

Authors:  Yih-Ling Tzeng; Karita D Ambrose; Susu Zughaier; Xiaoliu Zhou; Yoon K Miller; William M Shafer; David S Stephens
Journal:  J Bacteriol       Date:  2005-08       Impact factor: 3.490

3.  Immunogenicity of intranasally administered meningococcal native outer membrane vesicles in mice.

Authors:  N B Saunders; D R Shoemaker; B L Brandt; E E Moran; T Larsen; W D Zollinger
Journal:  Infect Immun       Date:  1999-01       Impact factor: 3.441

4.  Intranasal delivery of group B meningococcal native outer membrane vesicle vaccine induces local mucosal and serum bactericidal antibody responses in rabbits.

Authors:  David R Shoemaker; Nancy B Saunders; Brenda L Brandt; E Ellen Moran; Andrew D Laclair; Wendell D Zollinger
Journal:  Infect Immun       Date:  2005-08       Impact factor: 3.441

5.  Expression of sialic acid and polysialic acid in serogroup B Neisseria meningitidis: divergent transcription of biosynthesis and transport operons through a common promoter region.

Authors:  J S Swartley; J H Ahn; L J Liu; C M Kahler; D S Stephens
Journal:  J Bacteriol       Date:  1996-07       Impact factor: 3.490

6.  Transcriptional regulation of divergent capsule biosynthesis and transport operon promoters in serogroup B Neisseria meningitidis.

Authors:  Y L Tzeng; J S Swartley; Y K Miller; R E Nisbet; L J Liu; J H Ahn; D S Stephens
Journal:  Infect Immun       Date:  2001-04       Impact factor: 3.441

7.  Kinetic properties of the acylneuraminate cytidylyltransferase from Pasteurella haemolytica A2.

Authors:  I G Bravo; S Barrallo; M A Ferrero; L B Rodríguez-Aparicio; H Martínez-Blanco; A Reglero
Journal:  Biochem J       Date:  2001-09-15       Impact factor: 3.857

8.  The NorM efflux pump of Neisseria gonorrhoeae and Neisseria meningitidis recognizes antimicrobial cationic compounds.

Authors:  Corinne Rouquette-Loughlin; Steven A Dunham; Michael Kuhn; Jacqueline T Balthazar; William M Shafer
Journal:  J Bacteriol       Date:  2003-02       Impact factor: 3.490

9.  The (alpha2-->8)-linked polysialic acid capsule and lipooligosaccharide structure both contribute to the ability of serogroup B Neisseria meningitidis to resist the bactericidal activity of normal human serum.

Authors:  C M Kahler; L E Martin; G C Shih; M M Rahman; R W Carlson; D S Stephens
Journal:  Infect Immun       Date:  1998-12       Impact factor: 3.441

10.  The TolC-like protein of neisseria meningitidis is required for extracellular production of the repeats-in-toxin toxin FrpC but not for resistance to antimicrobials recognized by the Mtr efflux pump system.

Authors:  Nazia Kamal; Corinne Rouquette-Loughlin; William M Shafer
Journal:  Infect Immun       Date:  2007-10-08       Impact factor: 3.441
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